{\rtf1\deflang1033\deflangfe1033\margl720\margr720\margt360\margb360{\stylesheet{\fs20\lang1033\snext0 Normal;} {\s1\sb240\keepn{\*\pn \pnlvl1\pndec\pnprev1\pnstart1\pnsp144}\b\f0\fs30\lang1033 \sbasedon0\snext0 heading 1;} {\s2\sb200\keepn{\*\pn \pnlvl2\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs26\lang1033 \sbasedon0\snext0 heading 2;} {\s3\sb180\keepn{\*\pn \pnlvl3\pndec\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 3;} {\s4\sb160\keepn{\*\pn \pnlvl4\pnucltr\pnprev1\pnstart1\pnsp144{\pntxtb.}}\b\f0\fs22\lang1033 \sbasedon0\snext0 heading 4;} {\s5\sb140\keepn{\*\pn \pnlvl5\pncltr\pnprev1\pnstart1\pnsp144}\b\f0\fs20\lang1033 \sbasedon0\snext0 heading 5;} {\s6\tqc\lang1033\sbasedon0\snext6 footer;} {\*\cs16 \additive\super\sbasedon10 footnote reference;} {\*\cs18 \additive\sbasedon10 page number;}} {\fonttbl{\f0\fnil Times New Roman;}{\f1\fnil Courier New}{\f2005\fnil Courier New;}{\f2010\fnil Wingdings;}{\f2020\fnil Webdings;}{\f2\fnil 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COMMISSION\par\pard\plain\sa264\cf1\f51\fs20\qc Washington, D.C. 20549\~\par\pard\plain\sa264\cf1\f51\fs20\qc FORM 8-K\par\pard\plain\cf1\f51\fs20\b\qc CURRENT REPORT\par\pard\plain\cf1\f51\fs20\b\qc PURSUANT TO SECTION 13 OR 15(d) OF THE\par\pard\plain\cf1\f51\fs20\qc SECURITIES EXCHANGE ACT OF 1934 \par\pard\plain\fs16\par\pard\plain\sa264\cf1\f51\fs20\qc Date of Report (Date of earliest event reported): June 7, 2018 \par\pard\plain {\trowd\cellx2160\clbrdrb\brdrs\brdrcf1\cellx8640\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\b\qc TherapeuticsMD, Inc.\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx2160\clbrdrb\brdrs\brdrcf1\cellx8640\cellx10800\trrh248\row}}}\pard\plain\sa660\cf1\f51\fs20\qc (Exact Name of Registrant as Specified in its Charter) \par\pard\plain {\trowd\clbrdrb\brdrs\brdrcf1\cellx3456\cellx3672\clbrdrb\brdrs\brdrcf1\cellx7128\cellx7343\clbrdrb\brdrs\brdrcf1\cellx10800\trrh248 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\b\qc Nevada\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\b\qc 001-00100\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\b\qc 87-0233535\cell{ {\trowd\clbrdrb\brdrs\brdrcf1\cellx3456\cellx3672\clbrdrb\brdrs\brdrcf1\cellx7128\cellx7343\clbrdrb\brdrs\brdrcf1\cellx10800\trrh248\row}}} {\trowd\cellx3456\cellx3672\cellx7128\cellx7343\cellx10800\trrh495 \pard\plain\intbl\cf1\f51\fs20\qc (State or Other\par\pard\plain\intbl\cf1\f51\fs20\qc Jurisdiction of Incorporation)\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\qc (Commission File Number)\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\qc (IRS Employer \par\pard\plain\intbl\fs16\pard\plain\intbl\li110\ri110\cf1\f51\fs20\qc Identification No.)\cell{ {\trowd\cellx3456\cellx3672\cellx7128\cellx7343\cellx10800\trrh495\row}}}\pard\plain\sa264\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx2160\clbrdrb\brdrs\brdrcf1\cellx8640\cellx10800\trrh495 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\qc 6800 Broken Sound Parkway NW, Third Floor\par\pard\plain\intbl\cf1\f51\fs20\qc Boca Raton, FL 33487\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx2160\clbrdrb\brdrs\brdrcf1\cellx8640\cellx10800\trrh495\row}}} {\trowd\cellx2160\cellx8640\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\qc (Address of Principal Executive Office) (Zip Code)\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx2160\cellx8640\cellx10800\trrh248\row}}}\pard\plain\sa264\cf1\f51\fs20\qc \~Registrant\u8217?s telephone number, including area code: (561) 961-1900\par\pard\plain\cf1\f51\fs20\ql Check the appropriate box below if the Form 8-K filing is intended to simultaneously satisfy the filing obligation of the\plain\sa264\cf1\f51\fs20\ql registrant under any of the following provisions:\par\pard\plain\sa-242\cf1\f51\fs20\qj \u9744?\par\pard\plain\li550\sa264\cf1\f51\fs20\qj Written communications pursuant to Rule 425 under the Securities Act (17 CFR 230.425)\par\pard\plain\sa-242\cf1\f51\fs20\qj \u9744?\par\pard\plain\li550\sa264\cf1\f51\fs20\qj Soliciting material pursuant to Rule 14a-12 under the Exchange Act (17 CFR 240.14a-12)\par\pard\plain\sa-242\cf1\f51\fs20\qj \u9744?\par\pard\plain\li550\sa264\cf1\f51\fs20\qj Pre-commencement communications pursuant to Rule 14d-2(b) under the Exchange Act (17 CFR 240.14d-2(b))\par\pard\plain\sa-242\cf1\f51\fs20\qj \u9744?\par\pard\plain\li550\cf1\f51\fs20\qj Pre-commencement communications pursuant to Rule 13e-4(c) under the Exchange Act\~\plain\li550\cf1\f51\fs20\qj (17 CFR 240.13e-4(c))\plain\li550\sa264\cf1\f51\fs20\qj \~\par\pard\plain\cf1\f51\fs20\qj Indicate by check mark whether the registrant is an emerging growth company as defined in Rule 405 of the Securities Act of\plain\sa264\cf1\f51\fs20\qj 1933 (\u167? 230-405 of this chapter) or Rule 12b-2 of the Securities Exchange Act of 1934 (\u167?240.12b-2 of this chapter).\par\pard\plain\cf1\f51\fs20\ql Emerging growth company\plain\sa264\cf1\f51\fs20\ql \~\~\u9744?\par\pard\plain\cf1\f51\fs20\ql If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for\plain\cf1\f51\fs20\ql complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange\plain\cf1\f51\fs20\ql Act.\plain\sa264\cf1\f51\fs20\ql \~\~\u9744? \par\pard\plain {\trowd\cellx3564\cellx7235\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx3564\cellx7235\cellx10800\trrh248\row}}} \page \par\pard\plain {\trowd\clvertalc\cellx10800\trrh248 \pard\plain\intbl\brdrb\brdrs\cf1\f51\fs20\qc \~\cell{ {\trowd\clvertalc\cellx10800\trrh248\row}}}{\*\bkmkstart part_1_2_1}{\*\bkmkend part_1_2_1}{\*\bkmkstart item_1_31_1}{\*\bkmkend item_1_31_1} \pard\plain {\trowd\cellx1706\cellx10800\trrh495 \pard\plain\intbl\cf1\f51\fs20\b\ql Item 2.03\cell\pard\plain\intbl\cf1\f51\fs20\b\ql Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement\plain\intbl\cf1\f51\fs20\b\ql of a Registrant.\cell{ {\trowd\cellx1706\cellx10800\trrh495\row}}}\pard\plain\fi550\cf1\f51\fs20\qj On June 7, 2018, TherapeuticsMD, Inc., a Nevada corporation (the \u8220?\plain\cf1\f51\fs20\ul\qj Company\plain\cf1\f51\fs20\qj \u8221?), completed the first draw\plain\cf1\f51\fs20\qj down of $75 million under its previously announced $200 million term loan facility with MidCap Financial Trust, as agent and\plain\cf1\f51\fs20\qj as lender, and the additional lenders party thereto from time to time (the \u8220?\plain\cf1\f51\fs20\ul\qj Credit Agreement\plain\cf1\f51\fs20\qj \u8221?). The Company\plain\cf1\f51\fs20\qj intends to use the proceeds from the first draw down under the Credit Agreement to support the commercial launch of its\plain\cf1\f51\fs20\qj recently approved product, Imvexxy\u8482? (estradiol vaginal inserts) for the treatment of moderate-to-severe dyspareunia\plain\sa220\cf1\f51\fs20\qj (vaginal pain associated with sexual activity), a symptom of vulvar and vaginal atrophy (VVA), due to menopause.\par\pard\plain\fi550\cf1\f51\fs20\qj A summary of the material terms of the Credit Agreement is included in Item 1.01 of the Company\u8217?s Current\plain\sa220\cf1\f51\fs20\qj Report on Form 8-K, filed on May 3, 2018, and is incorporated herein by reference. \par\pard\plain {\trowd\cellx1706\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\b\ql Item 7.01\cell\pard\plain\intbl\cf1\f51\fs20\b\qj Regulation FD Disclosure\cell{ {\trowd\cellx1706\cellx10800\trrh248\row}}}\pard\plain\fi550\cf1\f51\fs20\qj On June 7, 2018, the Company issued a press release announcing the completion of the first draw down under the Credit\plain\cf1\f51\fs20\qj Agreement. The press release is furnished as Exhibit 99.1 hereto. The information included in this Item 7.01 and Exhibit 99.1\plain\cf1\f51\fs20\qj shall not be deemed \u8220?filed\u8221? for purposes of Section 18 of the Securities Exchange Act of 1934, as amended (the\plain\cf1\f51\fs20\qj \u8220?\plain\cf1\f51\fs20\ul\qj Exchange Act\plain\cf1\f51\fs20\qj \u8221?), or otherwise subject to the liabilities of that section, nor shall it be deemed incorporated by\plain\cf1\f51\fs20\qj reference in any filing under the Securities Act of 1933, as amended, or the Exchange Act, except as expressly set forth by\plain\sa220\cf1\f51\fs20\qj specific reference in such a filing.{\*\bkmkstart part_1_2_2}{\*\bkmkend part_1_2_2}{\*\bkmkstart item_1_47_1}{\*\bkmkend item_1_47_1} \par\pard\plain {\trowd\cellx1706\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\b\ql Item 9.01\cell\pard\plain\intbl\cf1\f51\fs20\b\ql Financial Statements and Exhibits.\cell{ {\trowd\cellx1706\cellx10800\trrh248\row}}} \pard\plain {\trowd\cellx1706\cellx3412\clvmgf\cellx10800\trrh248 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\qr (d)\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\i\ql Exhibits\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx1706\cellx3412\clvmgf\cellx10800\trrh248\row}}} {\trowd\cellx1706\cellx3412\clvmrg\cellx10800\trrh248 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\f0\fs16\ql \~\cell{ {\trowd\cellx1706\cellx3412\clvmrg\cellx10800\trrh248\row}}} {\trowd\cellx1706\cellx3412\cellx10800\trrh495 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql Exhibit\par\pard\plain\intbl\cf1\f51\fs20\ul\ql Number\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\par\pard\plain\intbl\cf1\f51\fs20\ul\ql Description\cell{ {\trowd\cellx1706\cellx3412\cellx10800\trrh495\row}}} {\trowd\cellx1706\cellx3412\cellx10800\trrh248 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx1706\cellx3412\cellx10800\trrh248\row}}} {\trowd\cellx1706\cellx3412\cellx10800\trrh968 \pard\plain\intbl\li110\ri110\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~99.1\cell\pard\plain\intbl\ul{\field{\*\fldinst HYPERLINK \\l "doc_1_2" }{\*\fldrslt\cf3\f51\fs20\ql Press Release from TherapeuticsMD, Inc., dated June 7, 2018, entitled}}\plain\intbl\ul{\field{\*\fldinst HYPERLINK \\l "doc_1_2" }{\*\fldrslt\cf3\f51\fs20\ql \u8220?TherapeuticsMD Announces Draw Down of $75 Million Under Term Loan}}\plain\intbl\ul{\field{\*\fldinst HYPERLINK \\l "doc_1_2" }{\*\fldrslt\cf3\f51\fs20\ql with MidCap Financial.\u8221?}}\cell{ {\trowd\cellx1706\cellx3412\cellx10800\trrh968\row}}}\pard\plain\sa264\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx3564\cellx7235\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx3564\cellx7235\cellx10800\trrh248\row}}} \page \par\pard\plain {\trowd\clvertalc\cellx10800\trrh248 \pard\plain\intbl\brdrb\brdrs\cf1\f51\fs20\qc \~\cell{ {\trowd\clvertalc\cellx10800\trrh248\row}}}{\*\bkmkstart part_1_2_3}{\*\bkmkend part_1_2_3}\pard\plain\sa220\cf1\f51\fs20\b\qc SIGNATURES\par\pard\plain\fi550\cf1\f51\fs20\qj Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed\plain\sa264\cf1\f51\fs20\qj on its behalf by the undersigned hereunto duly authorized. \par\pard\plain {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql Date: June 7, 2018\cell\pard\plain\intbl\cf1\f51\fs20\ql THERAPEUTICSMD, INC.\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx5400\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx6047\clbrdrb\brdrs\brdrcf1\cellx9827\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql By:\cell\pard\plain\intbl\cf1\f51\fs20\ql /s/ Daniel A. Cartwright\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx5400\cellx6047\clbrdrb\brdrs\brdrcf1\cellx9827\cellx10800\trrh248\row}}} {\trowd\cellx5400\cellx6047\cellx10799\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql Name:\cell\pard\plain\intbl\cf1\f51\fs20\ql Daniel A. Cartwright\cell{ {\trowd\cellx5400\cellx6047\cellx10799\trrh248\row}}} {\trowd\cellx5400\cellx6047\cellx10799\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql Title:\cell\pard\plain\intbl\cf1\f51\fs20\ql Chief Financial Officer\cell{ {\trowd\cellx5400\cellx6047\cellx10799\trrh248\row}}}\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx3564\cellx7235\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx3564\cellx7235\cellx10800\trrh248\row}}}\pard\plain\brdrb\brdrs\cf1\f51\fs20\ql \~ \page{\*\bkmkstart doc_1_2}{\*\bkmkend doc_1_2}\par\pard\plain\brdrb\brdrs\cf1\f51\fs2\ql \~\pard\plain\ul{\field{\*\fldinst HYPERLINK \\l "doc_1_1" }{\*\fldrslt\cf3\f51\fs20\ql TherapeuticsMD, Inc. 8-K}}\par\pard\plain\cf1\f51\fs20\ql \~\par\pard\plain\cf1\f51\fs20\b\qr Exhibit 99.1\par\pard\plain\cf1\f51\fs20\qr \~\par\pard\plain\cf1\f51\fs20\b\qr \~\par\qr{\*\shppict{\pict\pngblip\picw239\pich28\picscalex75\picscaley75\bliptag-8749102125 {\*\blipuid 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\par\pard\plain\sa176\cf1\f51\fs20\qj \~\par\pard\plain\sa132\cf1\f52\fs20\b\qj FOR IMMEDIATE RELEASE\par\pard\plain\sa132\cf1\f52\fs20\b\qc \~\par\pard\plain\sa176\cf1\f52\fs20\b\qc TherapeuticsMD Announces Draw Down of $75 Million Under Term Loan with MidCap Financial\~\par\pard\plain\cf1\f52\fs20\b\qj BOCA RATON, Fla. - June 7, 2018\plain\cf1\f52\fs20\qj - TherapeuticsMD, Inc. (NASDAQ: TXMD), an innovative women\u8217?s\plain\cf1\f52\fs20\qj healthcare company, today announced that the company has completed the first draw down of $75 million under its\plain\cf1\f52\fs20\qj previously announced $200 million term loan facility with MidCap Financial, managed by Apollo Capital Management,\plain\cf1\f52\fs20\qj L.P. The Company intends to use the proceeds from the financing to support the commercial launch of its recently\plain\cf1\f52\fs20\qj approved product, Imvexxy (estradiol vaginal inserts) for the treatment of moderate-to-severe dyspareunia (vaginal\plain\cf1\f52\fs20\qj pain associated with sexual activity), a symptom of vulvar and vaginal atrophy (VVA), due to menopause.\plain\sa176\cf1\f52\fs20\b\qj \~\par\pard\plain\sa176\cf1\f52\fs20\b\ql About\~TherapeuticsMD, Inc.\par\pard\plain\cf1\f52\fs20\qj TherapeuticsMD, Inc.\~is an innovative healthcare company focused on developing and commercializing products\plain\cf1\f52\fs20\qj exclusively for women. With its SYMBODA technology,\~TherapeuticsMD\~is developing advanced hormone therapy\plain\cf1\f52\fs20\qj pharmaceutical products to enable delivery of bio-identical hormones through a variety of dosage forms and\plain\cf1\f52\fs20\qj administration routes. The company has recently received FDA approval for TX-004HR, branded as IMVEXXY\plain\cf1\f52\fs20\qj (estradiol vaginal inserts), for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal\plain\cf1\f52\fs20\qj atrophy, due to menopause. The company\u8217?s late stage clinical pipeline includes TX-001HR for treatment of\plain\cf1\f52\fs20\qj moderate-to-severe vasomotor symptoms (VMS) due to menopause. The company also manufactures and distributes\plain\cf1\f52\fs20\qj branded and generic prescription prenatal vitamins as well as over-the-counter prenatal vitamins under the\plain\sa176\cf1\f52\fs20\qj vitaMedMD\u174?\~and BocaGreenMD\u174?\~brands.\par\pard\plain\sa176\cf1\f52\fs20\b\ql Forward-Looking Statements\par\pard\plain\cf1\f52\fs20\qj This press release by\~TherapeuticsMD, Inc.\~may contain forward-looking statements. Forward-looking statements may\plain\cf1\f52\fs20\qj include, but are not limited to, statements relating to TherapeuticsMD\u8217?s objectives, plans and strategies as well\plain\cf1\f52\fs20\qj as statements, other than historical facts, that address activities, events or developments that the company intends,\plain\cf1\f52\fs20\qj expects, projects, believes or anticipates will or may occur in the future. These statements are often characterized by\plain\cf1\f52\fs20\qj terminology such as \u8220?believes,\u8221? \u8220?hopes,\u8221? \u8220?may,\u8221? \u8220?anticipates,\u8221?\plain\cf1\f52\fs20\qj \u8220?should,\u8221? \u8220?intends,\u8221? \u8220?plans,\u8221? \u8220?will,\u8221? \u8220?expects,\u8221?\plain\cf1\f52\fs20\qj \u8220?estimates,\u8221? \u8220?projects,\u8221? \u8220?positioned,\u8221? \u8220?strategy\u8221? and similar\plain\cf1\f52\fs20\qj expressions and are based on assumptions and assessments made in light of management\u8217?s experience and\plain\cf1\f52\fs20\qj perception of historical trends, current conditions, expected future developments and other factors believed to be\plain\cf1\f52\fs20\qj appropriate. Forward-looking statements in this press release are made as of the date of this press release, and the\plain\cf1\f52\fs20\qj company undertakes no duty to update or revise any such statements, whether as a result of new information, future\plain\cf1\f52\fs20\qj events or otherwise. Forward-looking statements are not guarantees of future performance and are subject to risks\plain\cf1\f52\fs20\qj and uncertainties, many of which are outside of the company\u8217?s control. Important factors that could cause\plain\cf1\f52\fs20\qj actual results, developments and business decisions to differ materially from forward-looking statements are\plain\cf1\f52\fs20\qj described in the sections titled \u8220?Risk Factors\u8221? in the company\u8217?s filings with the\~Securities and\plain\cf1\f52\fs20\qj Exchange Commission, including its most recent Annual Report on Form 10-K and Quarterly Reports on Form 10-Q,\plain\cf1\f52\fs20\qj as well as reports on Form 8-K, and include the following: whether the FDA will approve the NDA for the\plain\cf1\f52\fs20\qj company\u8217?s TX-001HR product candidate and whether such approval will occur by the PDUFA target action\plain\cf1\f52\fs20\qj date; the company\u8217?s ability to maintain or increase sales of its products; the company\u8217?s ability to\plain\cf1\f52\fs20\qj develop and commercialize its hormone therapy drug candidates and obtain additional financing necessary therefor;\plain\cf1\f52\fs20\qj whether the company be able to comply with the covenants and conditions under its term loan agreement; the length,\plain\cf1\f52\fs20\qj cost and uncertain results of the company\u8217?s clinical trials; the potential of adverse side effects or other safety\plain\cf1\f52\fs20\qj risks that could preclude the approval of the company\u8217?s hormone therapy drug candidates or adversely affect\plain\cf1\f52\fs20\qj the commercialization of the company\u8217?s current or future approved products; the company\u8217?s reliance on\plain\cf1\f52\fs20\qj third parties to conduct its clinical trials, research and development and manufacturing; the availability of\plain\cf1\f52\fs20\qj reimbursement from government authorities and health insurance companies for the company\u8217?s products; the\plain\cf1\f52\fs20\qj impact of product liability lawsuits; the influence of extensive and costly government regulation; the volatility of the\plain\cf1\f52\fs20\qj trading price of the company\u8217?s common stock and the concentration of power in its stock ownership. PDF\plain\cf1\f52\fs20\qj copies of the company\u8217?s historical press releases and financial tables can be viewed and downloaded at its\plain\sa176\cf1\f52\fs20\qj website:\~www.therapeuticsmd.com/pressreleases.aspx.\par\pard\plain\sa176\cf1\f52\fs20\qc ###\par\pard\plain\sa176\cf1\f52\fs20\b\qj CONTACT\par\pard\plain\sa176\cf1\f52\fs20\b\ql Investor Contact\par\pard\plain\cf1\f52\fs20\ql Nichol Ochsner,\par\pard\plain\cf1\f52\fs20\ql Vice President Investor Relations\par\pard\plain\cf1\f52\fs20\ql 561-961-1900, ext. 2088\par\pard\plain\cf1\f52\fs20\ql Nochsner@TherapeuticsMD.com\plain\sa132\cf1\f52\fs20\b\ql \~\par\pard\plain\cf1\f51\fs20\ql \~ \par\pard\plain {\trowd\cellx3564\cellx7235\cellx10800\trrh248 \pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell\pard\plain\intbl\cf1\f51\fs20\ql \~\cell{ {\trowd\cellx3564\cellx7235\cellx10800\trrh248\row}}}\pard\plain\brdrb\brdrs\cf1\f51\fs20\b\ql \~}