0001564590-21-056434 | 10-Q | XBRL Viewer

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Document and Entity Information - shares	9 Months Ended
Document and Entity Information - shares	Sep. 30, 2021	Nov. 11, 2021
Cover [Abstract]
Document Type	10-Q
Amendment Flag	false
Document Quarterly Report	true
Document Transition Report	false
Document Period End Date	Sep. 30, 2021
Document Fiscal Period Focus	Q3
Document Fiscal Year Focus	2021
Current Fiscal Year End Date	--12-31
Entity File Number	001-00100
Entity Registrant Name	THERAPEUTICSMD, INC.
Entity Central Index Key	0000025743
Entity Tax Identification Number	87-0233535
Entity Incorporation, State or Country Code	NV
Entity Address, Address Line One	951 Yamato Road
Entity Address, Address Line Two	Suite 220
Entity Address, City or Town	Boca Raton
Entity Address, State or Province	FL
Entity Address, Postal Zip Code	33431
City Area Code	561
Local Phone Number	961-1900
Title of 12(b) Security	Common Stock, par value $0.001 per share
Trading Symbol	TXMD
Security Exchange Name	NASDAQ
Entity Current Reporting Status	Yes
Entity Interactive Data Current	Yes
Entity Filer Category	Non-accelerated Filer
Entity Small Business	true
Entity Emerging Growth Company	false
Entity Shell Company	false
Entity Common Stock, Shares Outstanding		424,928,670

CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Current assets:
Cash	$ 104,841	$ 80,486
Accounts receivable, net of allowance for credit losses of $1,351 and $1,118 as of September 30, 2021 and December 31, 2020, respectively	37,402	32,382
Inventory	7,362	7,993
Prepaid and other current assets	10,374	7,543
Total current assets	159,979	128,404
Fixed assets, net	1,388	1,942
License rights and other intangible assets, net	39,617	41,445
Right of use assets	8,391	9,566
Other non-current assets	253	253
Total assets	209,628	181,610
Current liabilities:
Current maturities of long-term debt	15,000
Accounts payable	19,592	21,068
Accrued expenses and other current liabilities	51,674	38,170
Total current liabilities	86,266	59,238
Long-term debt, net	171,738	237,698
Operating lease liabilities	8,226	8,675
Other non-current liabilities	758
Total liabilities	266,988	305,611
Commitments and contingencies (Note 9)
Stockholders' equity (deficit):
Preferred stock, par value $0.001; 10,000 shares authorized, none issued	0	0
Common stock, par value $0.001; 600,000 shares authorized, 424,879 and 299,765 issued and outstanding as of September 30, 2021 and December 31, 2020, respectively	425	300
Additional paid-in capital	950,615	754,644
Accumulated deficit	(1,008,400)	(878,945)
Total stockholders' deficit	(57,360)	(124,001)
Total liabilities and stockholders' equity	$ 209,628	$ 181,610

CONSOLIDATED BALANCE SHEETS (Parenthetical) - USD ($) shares in Thousands, $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Statement Of Financial Position [Abstract]
Accounts Receivable, Allowance for Credit Loss	$ 1,351	$ 1,118
Preferred Stock, Par or Stated Value Per Share	$ 0.001	$ 0.001
Preferred Stock, Shares Authorized	10,000	10,000
Preferred Stock, Shares Issued	0	0
Common Stock, Par or Stated Value Per Share	$ 0.001	$ 0.001
Common Stock, Shares Authorized	600,000	600,000
Common Stock, Shares, Issued	424,879	299,765
Common Stock, Shares, Outstanding	424,879	299,765

CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($) shares in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Total revenue, net	$ 25,406,000	$ 19,342,000	$ 68,273,000	$ 42,294,000
Cost of goods sold	5,282,000	3,279,000	14,101,000	10,394,000
Total gross profit	20,124,000	16,063,000	54,172,000	31,900,000
Operating expenses:
Selling and marketing	30,005,000	22,373,000	86,193,000	91,056,000
General and administrative	28,435,000	16,637,000	66,691,000	53,740,000
Research and development	1,605,000	2,027,000	5,666,000	8,038,000
Total operating expenses	60,045,000	41,037,000	158,550,000	152,834,000
Loss from operations	(39,921,000)	(24,974,000)	(104,378,000)	(120,934,000)
Other (expense) income:
Interest expense and other financing costs	(7,518,000)	(7,680,000)	(25,341,000)	(20,969,000)
Other income, net	19,000	42,000	264,000	466,000
Total other (expense), net	(7,499,000)	(7,638,000)	(25,077,000)	(20,503,000)
Loss before income taxes	(47,420,000)	(32,612,000)	(129,455,000)	(141,437,000)
Provision for income taxes	0	0	0	0
Net loss	$ (47,420,000)	$ (32,612,000)	$ (129,455,000)	$ (141,437,000)
Loss per common share, basic and diluted	$ (0.11)	$ (0.12)	$ (0.33)	$ (0.52)
Weighted average common shares, basic and diluted	422,216	272,565	388,111	271,969
Product [Member]
Total revenue, net	$ 24,469,000	$ 17,342,000	$ 67,102,000	$ 40,294,000
License [Member]
Total revenue, net	$ 937,000	$ 2,000,000	$ 1,171,000	$ 2,000,000

CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($) $ in Thousands	Total	Common Stock [Member]	Additional Paid-in Capital [Member]	Accumulated Deficit [Member]
Beginning balance, value at Dec. 31, 2019	$ 9,201	$ 271	$ 704,351	$ (695,421)
Beginning balance, shares at Dec. 31, 2019		271,177,000
Shares issued for exercise of options	72		72
Shares issued for exercise of options (in shares)		351,000
Shares issued for vested restricted stock units (in shares)		150,000
Share-based compensation	2,366		2,366
Net loss	(56,849)			(56,849)
Ending balance, value at Mar. 31, 2020	(45,210)	$ 271	706,789	(752,270)
Ending balance, shares at Mar. 31, 2020		271,678,000
Beginning balance, value at Dec. 31, 2019	9,201	$ 271	704,351	(695,421)
Beginning balance, shares at Dec. 31, 2019		271,177,000
Net loss	(141,437)
Ending balance, value at Sep. 30, 2020	(116,033)	$ 273	720,552	(836,858)
Ending balance, shares at Sep. 30, 2020		272,812,000
Beginning balance, value at Mar. 31, 2020	(45,210)	$ 271	706,789	(752,270)
Beginning balance, shares at Mar. 31, 2020		271,678,000
Shares issued for exercise of options	95	$ 1	94
Shares issued for exercise of options (in shares)		313,000
Shares issued for vested restricted stock units (in shares)		303,000
Share-based compensation	3,003		3,003
Net loss	(51,976)			(51,976)
Ending balance, value at Jun. 30, 2020	(94,088)	$ 272	709,886	(804,246)
Ending balance, shares at Jun. 30, 2020		272,294,000
Shares issued for exercise of warrants and options, net of cashless exercises	106	$ 1	105
Shares issued for exercise of warrants and options, net of cashless exercises (in shares)		518,000
Warrants issued in relation to debt financing agreement	7,428		7,428
Share-based compensation	3,133		3,133
Net loss	(32,612)			(32,612)
Ending balance, value at Sep. 30, 2020	(116,033)	$ 273	720,552	(836,858)
Ending balance, shares at Sep. 30, 2020		272,812,000
Beginning balance, value at Dec. 31, 2020	$ (124,001)	$ 300	754,644	(878,945)
Beginning balance, shares at Dec. 31, 2020	299,765,000	299,765,000
Shares issued for sale of common stock, net of cost, value	$ 150,899	$ 93	150,806
Shares issued for sale of common stock, net of cost, shares		92,870,000
Shares issued for exercise of warrants and options, net of cashless exercises	50		50
Shares issued for exercise of warrants and options, net of cashless exercises (in shares)		503,000
Shares issued for vested restricted stock units (in shares)		52,000
Share-based compensation	2,957		2,957
Net loss	(39,383)			(39,383)
Ending balance, value at Mar. 31, 2021	(9,478)	$ 393	908,457	(918,328)
Ending balance, shares at Mar. 31, 2021		393,190,000
Beginning balance, value at Dec. 31, 2020	$ (124,001)	$ 300	754,644	(878,945)
Beginning balance, shares at Dec. 31, 2020	299,765,000	299,765,000
Shares issued for exercise of options (in shares)	61,000
Net loss	$ (129,455)
Ending balance, value at Sep. 30, 2021	$ (57,360)	$ 425	950,615	(1,008,400)
Ending balance, shares at Sep. 30, 2021	424,879,000	424,879,000
Beginning balance, value at Mar. 31, 2021	$ (9,478)	$ 393	908,457	(918,328)
Beginning balance, shares at Mar. 31, 2021		393,190,000
Shares issued for sale of common stock, net of cost, value	163		163
Shares issued for sale of common stock, net of cost, shares		125,000
Shares issued for exercise of warrants and options, net of cashless exercises	228	$ 1	227
Shares issued for exercise of warrants and options, net of cashless exercises (in shares)		600,000
Shares issued for exercise of options	21		21
Shares issued for exercise of options (in shares)		54,000
Shares issued for vested restricted stock units		$ 1	(1)
Shares issued for vested restricted stock units (in shares)		929,000
Shares issued for sale of common stock related to employee stock purchase plan	134		134
Shares issued for sale of common stock related to employee stock purchase plan (in shares)		150,000
Share-based compensation	2,510		2,510
Net loss	(42,652)			(42,652)
Ending balance, value at Jun. 30, 2021	(49,074)	$ 395	911,511	(960,980)
Ending balance, shares at Jun. 30, 2021		395,048,000
Shares issued for sale of common stock, net of cost, value	31,819	$ 29	31,790
Shares issued for sale of common stock, net of cost, shares		28,770,000
Shares issued for exercise of options	3		3
Shares issued for exercise of options (in shares)		7,000
Shares issued for vested restricted stock units		$ 1	(1)
Shares issued for vested restricted stock units (in shares)		1,054,000
Share-based compensation	7,312		7,312
Net loss	(47,420)			(47,420)
Ending balance, value at Sep. 30, 2021	$ (57,360)	$ 425	$ 950,615	$ (1,008,400)
Ending balance, shares at Sep. 30, 2021	424,879,000	424,879,000

CONSOLIDATED STATEMENTS OF CASH FLOWS (Unaudited) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Cash flows from operating activities:
Net loss	$ (129,455)	$ (141,437)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation and amortization	3,091	3,039
Charges (credits) to provision for doubtful accounts	540	(47)
Inventory charge	1,082	5,744
Debt financing fees	4,158	1,645
Share-based compensation	12,779	8,502
Other	726	1,719
Changes in operating assets and liabilities:
Accounts receivable	(5,560)	384
Inventory	(451)	(3,816)
Prepaid and other current assets	(2,831)	2,038
Accounts payable	(1,476)	(3,072)
Accrued expenses and other current liabilities	13,504	(3,813)
Other non-current liabilities	758
Total adjustments	26,320	12,323
Net cash used in operating activities	(103,135)	(129,114)
Cash flows from investing activities:
Payment of patent related costs	(675)	(1,065)
Purchase of fixed assets	(34)	(39)
Net cash used in investing activities	(709)	(1,104)
Cash flows from financing activities:
Proceeds from sale of common stock, net of costs	182,881
Proceeds from exercise of options and warrants	302	272
Proceeds from sale of common stock related to employee stock purchase plan	134
Repayments of debt	(50,000)
Borrowings of debt		50,000
Payment of debt financing fees	(5,118)	(1,250)
Net cash provided by financing activities	128,199	49,022
Net increase (decrease) in cash	24,355	(81,196)
Cash, beginning of period	80,486	160,830
Cash, end of period	104,841	79,634
Supplemental disclosure of noncash financing activities:
Warrants issued in relation to debt financing agreement		7,428
Supplemental disclosure of cash flow information:
Interest paid	$ 19,675	$ 12,032

Basis of presentation and summary of significant accounting policies

9 Months Ended

Sep. 30, 2021

Accounting Policies [Abstract]

Basis of presentation and summary of significant accounting policies

1.	Basis of presentation and summary of significant accounting policies

General

TherapeuticsMD, Inc., a Nevada corporation (the “Company”), and its consolidated subsidiaries are referred to collectively in this Quarterly Report on Form 10-Q (“10-Q Report”) as “TherapeuticsMD,” “we,” “our” and “us.” This 10-Q Report includes our trademarks, trade names and service marks, such as TherapeuticsMD^®, vitaMedMD^®, BocaGreenMD^®, vitaCare^TM, IMVEXXY^®, BIJUVA^® and ANNOVERA^®, which are protected under applicable intellectual property laws and are the property of, or licensed to, the Company. Solely for convenience, trademarks, trade names and service marks referred to in this 10-Q Report may appear without the ^®, ^TM or ^SM symbols, but such references are not intended to indicate, in any way, that we will not assert, to the fullest extent under applicable law, our rights or the right of the applicable licensor to these trademarks, trade names and service marks. We do not intend our use or display of other parties’ trademarks, trade names or service marks to imply, and such use or display should not be construed to imply a relationship with, or endorsement or sponsorship of us by, these other parties.

We are a women’s healthcare company with a mission of creating and commercializing innovative products to support the lifespan of women from pregnancy prevention through menopause. At TherapeuticsMD, we combine entrepreneurial spirit, clinical expertise, and business leadership to develop and commercialize health solutions that enable new standards of care for women. Our solutions range from a patient-controlled, long-lasting contraceptive to advanced hormone therapy pharmaceutical products. We also have a portfolio of branded and generic prescription prenatal vitamins under the vitaMedMD and BocaGreenMD brands. Our portfolio of products focused on women’s health allows us to efficiently leverage our sales and marketing plan to grow our recently approved products.

Principles of consolidation

We prepared the consolidated financial statements included in this 10-Q Report following the requirements of the United States (“U.S.”) Securities and Exchange Commission (“SEC”) for interim reporting. As permitted under those rules, certain notes or other financial information that are normally required by accounting principles generally accepted in the U.S. (“U.S. GAAP”) can be condensed or omitted.

Revenues, expenses, assets, liabilities, and equities can vary during each quarter of the year. Therefore, the results and trends in these interim financial statements may not be representative of those for the full year. In our opinion, all adjustments necessary for a fair statement of the financial statements, which are of a normal and recurring nature, have been made for the interim periods reported. The information included in this 10-Q Report should be read in conjunction with the consolidated financial statements and accompanying notes included in our 2020 Annual Report on Form 10-K (“2020 10-K Report”). Certain amounts in the consolidated financial statements and accompanying notes may not add due to rounding, and all percentages have been calculated using unrounded amounts.

Risks and uncertainties related to COVID-19

We continue to be subject to risks and uncertainties in connection with the COVID-19 pandemic. The extent of the future impact of the COVID-19 pandemic on our business continues to be highly uncertain and difficult to predict. The ultimate global recovery from the pandemic will be dependent on, among other things, actions taken by governments and businesses to contain and combat the virus, including any variant strains, the speed and effectiveness of vaccine production and global distribution, as well as how quickly, and to what extent, normal economic and operating conditions can resume on a sustainable basis globally.

Since the early phase of the COVID-19 pandemic, we have been using substantial virtual options to ensure business continuity. One of our subsidiaries, vitaCare^™ Prescription Services, Inc. (“vitaCare Prescription Services”), a Florida corporation, assists patients in obtaining easy and convenient access to their prescriptions for products at a pharmacy of their choice, including via home delivery pharmacy options. We have also partnered with independent community pharmacies and multiple third-party online pharmacies and telemedicine providers that focus on contraception or menopause which provide patients real-time access to both diagnosis and treatment. We continue to support prescribers’ needs with samples and product materials through our sales force. If access is restricted, we have mailing options in place for these materials. We also have business continuity plans and infrastructure in place that allows for live virtual e-detailing of our products.

As part of our response to the COVID-19 pandemic, we implemented measures to reduce marketing expenses for 2020. We also implemented cost saving measures in 2020, which included negotiating lower fees or suspending services from third party vendors; implementing a company-wide hiring restriction; delaying or cancelling non-critical information technology projects; and eliminating non-essential travel, entertainment, meeting, and event expenses. In addition, we are planning to implement a significant cost savings initiative that is designed to reduce our annual costs in 2022 by at least $40.0 million. This figure does not include cost savings from, or the costs associated with the sale of an interest in vitaCare Prescription Services, which annualized cost savings are estimated at approximately $20.0 million.

The full impact of the COVID-19 pandemic continues to evolve. However, we remain committed to the execution of our corporate goals, despite the ongoing COVID-19 pandemic, as demonstrated in part by the increase in product revenue throughout 2021. As of the date of issuance of these consolidated financial statements, the future extent to which the COVID-19 pandemic may continue to materially impact our financial condition, liquidity, or results of operations remains uncertain. We are continuing to assess the effect of the COVID-19 pandemic on our operations by monitoring the spread of COVID-19 and the various actions implemented to combat the pandemic throughout the world. Even after the COVID-19 pandemic has subsided, we may continue to experience adverse impacts to our business as a result of any economic recession or depression that has occurred or may occur in the future.

While we currently believe that our COVID-19 contingency plan has the ability to mitigate many of the negative effects of the COVID-19 pandemic on our business, the severity of the impact of the COVID-19 pandemic on our business will depend on a number of factors, including, but not limited to, the duration and severity of the pandemic, the duration of “social distancing” orders, the ability of our sales force to access healthcare providers to promote our products, increases in unemployment, which could reduce access to commercial health insurance for our patients, thus limiting payer coverage for our products, and the impact of the pandemic on our global supply chain, all of which remain uncertain. Our future results of operations and liquidity could be materially adversely affected by delays in payments of outstanding receivable amounts beyond normal payment terms, supply chain disruptions, uncertain demand, and the impact of any initiatives or programs that we may undertake to address financial and operations challenges that we may face.

Going Concern

As of the filing date of this Quarterly Report on Form 10-Q, our cash balance was above the $60.0 million balance as required by the Financing Agreement described below in Note 8. Based on our current projections, we will need to raise additional capital to remain in compliance with this minimum cash balance covenant for the next twelve months from the issuance of these financial statements. To address our projected capital needs, we are pursuing various equity financing and other alternatives including the sale of an interest in vitaCare Prescription Services for which we commenced a sale process. The equity financing alternatives may include the private placement of equity, equity-linked, or other similar instruments or obligations with one or more investors, lenders, or other institutional counterparties or an underwritten public equity or equity-linked securities offering. Our ability to sell equity securities may be limited by market conditions. To the extent that we raise additional capital through the sale of such securities, the ownership interests of our existing stockholders will be diluted, and the terms of these new securities may include liquidation or other preferences that adversely affect the rights of our existing stockholders.

Along with considering additional financings, we have reviewed numerous potential scenarios in connection with steps that we may take to reduce our operating expenses. Based on our analysis, we believe that our existing cash reserves along with potential proceeds from the sale of certain non-core assets of the Company and proceeds from potential future financings, if available to us, would be sufficient to meet our cash needs arising in the ordinary course of business for the next twelve months from the date of this Quarterly Report on Form 10-Q.

If we are unsuccessful with future financings and if the successful commercialization of IMVEXXY, BIJUVA, or ANNOVERA is delayed, or the continued impact of the COVID-19 pandemic or issues in our supply chains related to our third party contract manufacturers on our business is worse than we anticipate, our existing cash reserves would be insufficient to maintain compliance with the Financing Agreement covenants or satisfy our liquidity requirements until we are able to successfully commercialize IMVEXXY, BIJUVA, and ANNOVERA. See also Note 3- Inventory for additional information regarding risks associated with our contract manufacturers, particularly for ANNOVERA. The presence of these projected factors in conjunction with the uncertainty of the capital markets raises substantial doubt about the Company's ability to continue as a going concern for the next twelve months from the issuance of these financial statements. Additionally, if circumstances were to require our independent registered public accounting firm to include a going concern uncertainty in their report on our annual consolidated financial statements, such matter would also take us out of compliance with certain of the Financing Agreement covenants. If we are unable to achieve any of the total minimum net revenue requirements or otherwise comply with any other covenant of the Financing Agreement, all or a portion of our obligations under the Financing Agreement may be declared immediately due and payable, which would have an adverse effect on our business, results of operations and financial condition.

The accompanying unaudited consolidated financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.

Significant accounting policies

The significant accounting policies we use for quarterly financial reporting are disclosed in Note 2, Summary of Significant Accounting Policies of the accompanying notes to the consolidated financial statements included in our 2020 10-K Report, and in the section below.

Accounting standards issued but not yet adopted

There have been no recently issued accounting standards not yet adopted by us which are expected, upon adoption, to have a material impact on our consolidated financial statements or processes.

Reclassification

Certain amounts, including type of operating expenses, reported in prior periods in the financial statements have been reclassified to conform to the current period’s presentation.

Accounts receivable

9 Months Ended

Sep. 30, 2021

Receivables [Abstract]

Accounts receivable

2.	Accounts receivable

We extend credit on an unsecured basis to most of our customers. Our exposure to credit losses may increase if our customers are adversely affected by changes in healthcare laws, coverage, and reimbursement, economic pressures or uncertainty associated with local or global economic recessions, disruption associated with the current COVID-19 pandemic, or other customer-specific factors. While we actively manage our credit exposure and work to respond to both changes in our customers’ financial conditions or macroeconomic events, there can be no guarantee we will be able to mitigate all of these risks successfully. Although we have historically not experienced significant credit losses, it is possible that there could be a material adverse impact from potential adjustments of the carrying amount of trade receivables in the future.

We review accounts receivable for uncollectible accounts and provide an allowance for doubtful accounts, which is based upon a review of outstanding receivables, historical collection information, reasonable supportable forecasts and existing economic conditions and we record an allowance that presents the net amount expected to be collected. We evaluate trade accounts receivable for delinquency. We write off delinquent receivables against our allowance for doubtful accounts based on individual credit evaluations, the results of collection efforts, and specific circumstances of customers. We record recoveries of accounts previously written off when received as an increase in the allowance for doubtful accounts. To the extent data we use to calculate these estimates does not accurately reflect bad debts, adjustments to these reserves may be required.

The following sets forth activities in our allowance for credit losses (in thousands):

	Total
Balance as of January 1, 2021	$	1,118
Charges to provision for credit losses		540
Write-off of uncollectible receivables		(307	)
Balance as of September 30, 2021	$	1,351

Inventory

9 Months Ended

Sep. 30, 2021

Inventory Disclosure [Abstract]

Inventory

We rely on third parties to manufacture our finished products, and we have entered into long-term supply agreements for the manufacture of ANNOVERA, IMVEXXY, and BIJUVA. We do not have a long-term supply agreement for the manufacture of our prescription vitamins. Additionally, we do not have long-term contracts for the supply of the active pharmaceutical ingredient (“API”) used in ANNOVERA and BIJUVA.

One of our third party contract manufacturers that manufactures ANNOVERA has recently experienced an increase in difficulties with the manufacturing process for ANNOVERA, which has resulted in batch failures. The challenges are multifactorial and include variability in raw material supply and normal manufacturing variation due to a semi-manual process. This has recently resulted in challenges to supply ANNOVERA consistently within the approved specification at a rate that meets the projected demand for ANNOVERA. To mitigate the manufacturing challenges, in August 2021 we filed a supplemental New Drug Application with the U.S. Food and Drug Administration (“FDA”) to modify the manufacturing (testing) specifications for ANNOVERA to allow for normal manufacturing variation that would increase the consistency of manufacturing and supply of ANNOVERA. There can be no

assurance that such a modification will be approved by the FDA. If the FDA fails to approve the requested modification by the Prescription Drug User Fee Act (“PDUFA”) date of December 12, 2021, our third party contract manufacturer may not be able to supply us with sufficient ANNOVERA to adequately supply the market or generate sufficient revenue to meet the covenants under the Financing Agreement. If we are unable to achieve any of the total minimum net revenue requirements or otherwise comply with any other covenant of the Financing Agreement, all or a portion of our obligations under the Financing Agreement may be declared immediately due and payable, which would have an adverse effect on our business, results of operations and financial condition.

If any of our third party contract manufacturers or any suppliers of raw materials or API experience further difficulties, do not comply with the terms of an agreement between us, or do not devote sufficient time, energy, and care to providing our manufacturing needs, we could experience additional interruptions in the supply of our products, which may have a material adverse impact on our revenue, results of operations and financial position and ability to meet our revenue and other covenants under our Financing Agreement.

Our inventory consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Raw materials	$	3,487	$	4,423
Work in process		688		220
Finished products		3,187		3,350
Inventory	$	7,362	$	7,993

Prepaid and other current assets

9 Months Ended

Sep. 30, 2021

Prepaid Expense And Other Assets Current [Abstract]

Prepaid and other current assets

4.	Prepaid and other current assets

Our prepaid and other current assets consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Insurance	$	3,801	$	2,568
Paragraph IV legal proceeding costs		2,858		—
Other		3,715		4,975
Prepaid and other current assets	$	10,374	$	7,543

Fixed assets

9 Months Ended

Sep. 30, 2021

Property Plant And Equipment [Abstract]

Fixed assets

5.	Fixed assets

Our fixed assets, net consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Furniture and fixtures	$	1,407	$	1,407
Computer and office equipment		1,855		1,784
Computer software		375		412
Leasehold improvements		80		80
Fixed assets		3,717		3,683
Less: accumulated depreciation and amortization		2,329		1,741
Fixed assets, net	$	1,388	$	1,942

We recorded depreciation expense of $0.2 million for the three months ended September 30, 2021 and 2020, and $0.6 million for the nine months ended September 30, 2021 and 2020.

Licensed rights and other intangible assets

9 Months Ended

Sep. 30, 2021

Goodwill And Intangible Assets Disclosure [Abstract]

Licensed rights and other intangible assets

6.Licensed rights and other intangible assets

The following provides information about our license rights and other intangible assets, net (in thousands):

	September 30, 2021						December 31, 2020
	Gross						Gross
	Carrying		Accumulated				Carrying		Accumulated
	Amount		Amortization		Net		Amount		Amortization		Net
Licensed rights and intangible assets subject to amortization:
License rights	$	40,000	$	6,070	$	33,930	$	40,000	$	3,803	$	36,197
Hormone therapy drug patents		4,732		985		3,747		4,045		749		3,296
Hormone therapy drug patents applied and pending approval		1,596		—		1,596		1,629		—		1,629
License rights and other intangible assets subject to amortization		46,328		7,055		39,273		45,674		4,552		41,122
Intangible assets not subject to amortization:
Trademarks/trade name rights		344		—		344		323		—		323
License rights and other intangible assets, net	$	46,672	$	7,055	$	39,617	$	45,997	$	4,552	$	41,445

Licensed rights

We recorded amortization expense related to the exclusive license rights agreement (the “Population Council License Agreement”) with Population Council of $0.8 million for the three months ended September 30, 2021 and 2020, and $2.3 million for the nine months ended September 30, 2021 and 2020.Other intangible assets

As of September 30, 2021, we had a total of 87 patents, of which 46 were domestic. As of December 31, 2020, we had a total of 77 patents, of which 38 were domestic. We recorded amortization expense related to patents of $0.1 million for the three months ended September 30, 2021 and 2020, and $0.2 million for the nine months ended September 30, 2021 and 2020, respectively.

We use a combination of qualitative and quantitative factors to assess licensed rights and intangible assets for impairment. As a result of performing these assessments, we determined that no impairment existed as of September 30, 2021 and, therefore, recorded no write-downs to any of our licensed rights and other intangible assets. However, during the nine months ended September 30, 2020, we wrote off $584,509 in costs related to trademarks and patents.

Accrued expenses and other current liabilities

9 Months Ended

Sep. 30, 2021

Payables And Accruals [Abstract]

Accrued expenses and other current liabilities

7.	Accrued expenses and other current liabilities

Other accrued expenses and other current liabilities consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Payroll and related costs	$	14,346	$	11,179
Rebates		15,421		11,011
Sales returns and coupons		3,200		7,057
Sales and marketing		6,223		228
Wholesale distributor fees		4,626		2,632
Professional fees		2,477		925
Other accrued expenses and current liabilities		5,381		5,138
Accrued expenses and other current liabilities	$	51,674	$	38,170

Debt

9 Months Ended

Sep. 30, 2021

Debt Disclosure [Abstract]

Debt

We are party to a Financing Agreement, as amended (the “Financing Agreement”), with Sixth Street Specialty Lending, Inc., as administrative agent (the “Administrative Agent”), various lenders from time-to-time party thereto, and certain of our subsidiaries party thereto from time to time as guarantors. Interest on amounts borrowed under the Financing Agreement is due and payable quarterly in arrears, and the Financing Agreement matures on March 31, 2024.

In January 2021, we entered into Amendment No. 7 to the Financing Agreement (“Amendment No. 7”) pursuant to which, among other amendments, the minimum quarterly product net revenue requirements attributable to commercial sales of IMVEXXY, BIJUVA, and ANNOVERA for the fiscal quarters ending March 31, 2021 and June 30, 2021 were reduced, and we paid an amendment financing fee of $5.0 million, which was included as a component of deferred financing fees in long-term debt in the accompanying consolidated balance sheets. Additionally, in connection with entering into Amendment No. 7, the warrants issued to the Administrative Agent and the lenders under the Financing Agreement on August 5, 2020 were further amended to provide for an additional adjustment to the exercise price if we conducted certain dilutive issuances prior to March 31, 2021. No such adjustments were made to the exercise price of these warrants prior to the expiration of such period.

In March 2021, we entered into Amendment No. 8 to the Financing Agreement (“Amendment No. 8”) pursuant to which, among other amendments, the minimum quarterly product net revenue requirements attributable to commercial sales of IMVEXXY, BIJUVA, and ANNOVERA were revised, the amortization and prepayment terms of the borrowings under the Financing Agreement were revised, and the Administrative Agent consented to a framework for our potential disposition of our vitaCare Prescription Services business. With respect to amortization and prepayment terms of the borrowings under the Financing Agreement, in connection with Amendment No. 8, we (i) repaid $50.0 million in principal under the Financing Agreement during the three months ended March 31, 2021, plus a 5.0% prepayment fee and (ii) agreed to make additional quarterly principal repayments plus the prepayment fees described below starting on March 31, 2022 through March 31, 2024. Additionally, in connection with Amendment No. 8, the prepayment fees on principal amounts being prepaid under the Financing Agreement were revised as follows: (i) 30.0% of the principal amount being repaid through March 31, 2022 (excluding the scheduled $5.0 million principal repayment on such date, which is subject to a 5.0% prepayment fee); (ii) 5.0% of the principal amount being repaid from April 1, 2022 through March 31, 2023; (iii) 3.0% of the principal amount being repaid from April 1, 2023 through March 31, 2024; and (iv) thereafter, none, in each case subject to certain limited exceptions, including with respect to a repayment in full of the obligations under the Financing Agreement.

Our debt consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Financing Agreement	$	200,000	$	250,000
Less: deferred financing fees		13,262		12,302
Debt, net		186,738		237,698
Current maturities of long-term debt		15,000		—
Long-term debt	$	171,738	$	237,698

Our future principal payments under the Financing Agreement are as follows (in thousands), excluding the prepayment fees described above:

Due on
	March 31,		June 30,		September 30,		December 31,		Total
2022	$	5,000	$	5,000	$	5,000	$	10,000	$	25,000
2023		10,000		41,250		41,250		41,250		133,750
2024		41,250		—		—		—		41,250
									$	200,000

Interest and financing costs

Interest expense and other financing costs consisted of the following (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
Interest expense	$	5,391	$	6,727	$	17,175	$	19,324
Interest prepayment fees		650		—		4,008		—
Financing fees amortization		1,477		953		4,158		1,645
Interest expense and other financing costs	$	7,518	$	7,680	$	25,341	$	20,969

Both Amendment No. 7 and No. 8 were accounted for as debt modification in accordance with U.S. GAAP. Accordingly, the unamortized deferred financing fees at each amendment date and the financing fee of $5.0 million for Amendment No. 7 are being deferred. These deferred financing fees are being amortized over the remining term of our Financing Agreement.

The estimated future amortization of our deferred financing fees is as follows (in thousands):

Year Ending December 31,
2021 (3 months)	$	1,532
2022		6,346
2023		4,990
2024		394
	$	13,262

Debt covenants compliance

The Financing Agreement requires us to have a minimum unrestricted cash balance of $60.0 million. As of the filing date of this 10-Q Report, our cash balance was above the required minimum balance. Based on our current projections, we will need to raise additional capital to remain in compliance with the minimum cash balance covenant for the next twelve months from the issuance of the consolidated financial statements included in this 10-Q Report. See Note 1 – Basis of presentation and summary of significant accounting policies - Going Concern above.

The Financing Agreement also requires us to maintain certain minimum quarterly product net revenue requirements and several other restrictive covenants, which could also be affected by the continued impact of the COVID-19 pandemic or issues in our supply chains related to our third-party contract manufacturers. These and other terms in the Financing Agreement must be monitored closely for compliance and could restrict our ability to grow our business or enter into transactions that we believe would be beneficial to our business. If we are unable to maintain the minimum unrestricted cash balance, achieve any of the total minimum net revenue requirements or otherwise comply with any other covenant of the Financing Agreement, all or a portion of our obligations under the Financing Agreement may be declared immediately due and payable, which would have an adverse effect on our business, results of operations and financial condition. As of September 30, 2021, we were in compliance, in all material respects, with our covenants under the Financing Agreement.

Commitments and contingencies

9 Months Ended

Sep. 30, 2021

Commitments And Contingencies Disclosure [Abstract]

Commitments and contingencies

9.	Commitments and contingencies

Minimum purchase commitments

We have manufacturing and supply agreements whereby we are required to purchase from Catalent, Inc. (“Catalent”) a minimum number of units of BIJUVA and IMVEXXY softgels during each respective annual contract year. The annual contract period for BIJUVA and IMVEXXY ends each April and July, respectively. If the minimum order quantities of BIJUVA or IMVEXXY are not met, we are required to pay a minimum commitment fee equal to 50% or 60%, respectively, of the difference between the total amount we would have paid if the minimum requirement had been fulfilled and the total amount of purchases of BIJUVA or IMVEXXY during each product’s respective contract year.

Additionally, with another third-party manufacturer, we have a manufacturing and supply agreement whereby we are required to purchase a minimum number of units of ANNOVERA during a contract year. The annual contract period for ANNOVERA ends each August. If the minimum order quantities of ANNOVERA are not met, we are required to pay a minimum commitment fee equal to the

difference between the total amount we would have paid if the minimum requirement had been fulfilled and the total amount of purchases of ANNOVERA during the contract year.

For each of the three annual contract years ending in 2021, we have met our minimum purchase number of units in all material respects. We believe that minimum commitment fees that we may pay, if any, will not have a material impact to our financial position and operating results. For annual contract years ending in 2022 and thereafter, we will continue to evaluate whether we will be able to meet each annual contract year’s respective minimum purchase commitment and will record a liability for estimated minimum commitment fees if we believe that we will not be able to reasonably meet the minimum purchase commitment.

Legal proceedings

In February 2020, we received a Paragraph IV certification notice letter (the “IMVEXXY Notice Letter”) regarding an Abbreviated New Drug Application (“ANDA”) submitted to FDA by Teva Pharmaceuticals USA, Inc. (“Teva”). The ANDA seeks approval from FDA to commercially manufacture, use, or sell a generic version of the 4 mcg and 10 mcg doses of IMVEXXY. In the IMVEXXY Notice Letter, Teva alleges that TherapeuticsMD patents listed in FDA’s Orange Book that claim compositions and methods of IMVEXXY (the “IMVEXXY Patents”), are invalid, unenforceable, and/or will not be infringed by Teva’s commercial manufacture, use, or sale of its proposed generic drug product. The IMVEXXY Patents identified in the IMVEXXY Notice Letter expire in 2032 or 2033. In April 2020, we filed a complaint for patent infringement against Teva in the United States District Court for the District of New Jersey arising from Teva’s ANDA filing with the FDA. We are seeking, among other relief, an order that the effective date of any FDA approval of Teva’s ANDA would be a date no earlier than the expiration of the IMVEXXY Patents and equitable relief enjoining Teva from infringing the IMVEXXY Patents. Teva has filed its answer and counterclaim to the complaint, alleging that the IMVEXXY Patents are invalid and not infringed. In July 2021, following a proposal by Teva, the District Court entered an order temporarily staying all proceedings in the IMVEXXY litigation, which order was filed under seal. On September 2, 2021, the District Court made available a public version of the order following the parties’ agreement to a consent motion to redact information Teva contended was confidential. The order provides that the statutory stay that prevents FDA from granting final approval of the ANDA for 30 months from the date of the Notice Letter will be extended for the number of days that the stay of the IMVEXXY litigation is in place. The length of the stay of the IMVEXXY litigation is dependent on further action by Teva.

In March 2020, we received a Paragraph IV certification notice letter (the “BIJUVA Notice Letter”) regarding an ANDA submitted to FDA by Amneal Pharmaceuticals (“Amneal”). The ANDA seeks approval from FDA to commercially manufacture, use, or sell a generic version of BIJUVA. In the BIJUVA Notice Letter, Amneal alleges that TherapeuticsMD patents listed in FDA’s Orange Book that claim compositions and methods of BIJUVA (the “BIJUVA Patents”) are invalid, unenforceable, and/or will not be infringed by Amneal’s commercial manufacture, use, or sale of its proposed generic drug product. The BIJUVA Patents identified in the BIJUVA Notice Letter expire in 2032. In April 2020, we filed a complaint for patent infringement against Amneal in the United States District Court for the District of New Jersey arising from Amneal’s ANDA filing with FDA. We are seeking, among other relief, an order that the effective date of any FDA approval of Amneal’s ANDA would be a date no earlier than the expiration of the BIJUVA Patents and equitable relief enjoining Amneal from infringing the BIJUVA Patents. Amneal has filed its answer and counterclaim to the complaint, alleging that the BIJUVA Patents are invalid and not infringed. A trial date has not been set. In February 2021, the District Court entered an order temporarily staying all proceedings in the BIJUVA litigation. The District Court stay also extends the 30-month stay for the period in which the BIJUVA litigation has been stayed.

As of September 30, 2021, in the aggregate, we have incurred and recorded paragraph IV legal proceeding costs amounting to $2.9 million in prepaid expenses and other current assets in the accompanying consolidated balance sheets since we believe that we will successfully prevail in these two legal proceedings. Upon the successful conclusion of each of the above legal proceeding, the related capitalized legal costs for that legal proceeding will be reclassified to patents, in license rights, and other intangible assets, net in the accompanying consolidated balance sheets and such costs will be amortized over the remaining useful of the respective patent. If we are unsuccessful in either one of the above legal proceedings, then the related capitalized legal costs and respective unamortized patent costs for that legal proceeding will be immediately expensed in the period in which we become aware of unsuccessful legal proceeding.

Stockholders’ Equity (Deficit)

9 Months Ended

Sep. 30, 2021

Equity [Abstract]

Stockholders’ Equity (Deficit)

10.	Stockholders’ equity (deficit)

Common stock

In November 2020, we entered into an at-the-market offering program (the “2020 ATM Program”) relating to shares of our common stock. The 2020 ATM Program permitted us to offer and sell shares of our common stock having an aggregate offering price of up to $50.0 million from time to time through or to the sales agent under the 2020 ATM Program. Sales of our common stock were permitted to be made from time to time in at-the-market offerings as defined in Rule 415 of the Securities Act of 1933, as amended (the “Securities Act”), including by means of ordinary broker’s transactions on the Nasdaq Stock Exchange or otherwise at market

prices prevailing at the time of sale, at prices related to prevailing market prices, or as otherwise agreed to with the sales agent. The sales agent was entitled to compensation at a fixed commission rate of 3.0% of the aggregate gross sales price per share sold. As of February 8, 2021, sales of shares of our common stock under the 2020 ATM Program were completed when we sold an aggregate total of 28,600,689 shares of our common stock at an average sale price of $1.75 per share. For the 2020 ATM Program, we received net proceeds of $48.1 million, after deducting the discounts and commissions to the sales agent and estimated offering expenses.

In February 2021, we closed on an underwritten public offering of our common stock, pursuant to which we issued 59,459,460 shares of our common stock at an offering price of $1.85 per share, and we received net proceeds of $96.6 million, after deducting the underwriting discounts and commissions and estimated offering expenses.

In March 2021, we entered into an at-the-market equity offering program (the “2021 ATM Program”) relating to shares of our common stock. The 2021 ATM Program permits us to offer and sell shares of our common stock having an aggregate offering price of up to $100.0 million from time to time through or to the sales agent under the 2021 ATM Program. Sales of our common stock may be made from time to time in at-the-market offerings as defined in Rule 415 of the Securities Act, including by means of ordinary broker’s transactions on the Nasdaq Stock Exchange or otherwise at market prices prevailing at the time of sale, at prices related to prevailing market prices, or as otherwise agreed to with the sales agent. The sales agent will be entitled to compensation at a fixed commission rate of 3.0% of the aggregate gross sales price per share sold. The sales agent is not required to sell any specific number or dollar amounts of securities but will act as sales agent and use commercially reasonable efforts to sell on our behalf all of the shares of common stock requested to be sold by us, consistent with its normal trading and sales practices, on mutually agreed terms between us and the sales agent. Through September 30, 2021, we have sold a total of 33,705,315 shares of our common stock under the 2021 ATM Program at an average sale price of $1.21 per share and we received estimated net proceeds of $38.8 million, after deducting discounts and commissions to the sales agent and estimated offering expenses. Subsequently, through the date of this 10-Q Report, we have not sold any additional shares of our common stock under the 2021 ATM Program. Future sales, if any, under the 2021 ATM Program will depend on a variety of factors, including among others, market conditions, the trading price of our common stock, determinations by us of the appropriate sources of funding, and potential uses of funding available to us.

Warrants

The following tables summarizes the status of our outstanding and exercisable warrants and related transactions since December 31, 2020 (in thousands, except weighed average exercise price and weighted average remaining contractual life data):

	Warrants outstanding and exercisable
	Warrants			Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)
As of December 31, 2020		6,535		$	1.55	$	1,041		7.3
Exercised		(1,163	)		0.31
Expired		(245	)		4.80
As of September 30, 2021		5,127		$	1.52	$	-		8.6

The aggregate intrinsic value of warrants exercised during the nine months ended September 30, 2021 was $1.1 million.

Share-based compensation payment plans

At the 2021 annual meeting of stockholders of the Company, held on May 27, 2021, our stockholders among other things approved the First Amendment to the TherapeuticsMD, Inc. 2019 Stock Incentive Plan (the “2019 Plan”) to increase the number of shares of our common stock available under the 2019 Plan by 22,475,000 shares. As of September 30, 2021, there were 10,182,803 shares of common stock available for issuance under the 2019 Plan, consisting of (i) new shares, (ii) unallocated shares previously available for issuance under the 2012 Stock Incentive Plan (the “2012 Plan”) that were not then subject to outstanding “Awards” (as defined in the 2012 Plan), and (iii) unallocated shares previously available for issuance under the 2009 Long-Term Incentive Compensation Plan (the “2009 Plan” and together with the 2019 Plan and the 2012 Plan, the “Plans”) that were not then subject to outstanding “Awards” (as defined in the 2009 Plan). Any shares subject to outstanding options or other equity “Awards” under the 2019 Plan, the 2012 Plan and the 2009 Plan that are forfeited, expire or otherwise terminate without issuance of the underlying shares, or if any such Award is settled for cash or otherwise does not result in the issuance of all or a portion of the shares subject to such Award (other than shares tendered or withheld in connection with the exercise of an Award or the satisfaction of withholding tax liabilities), the shares to which

those Awards were subject, shall, to the extent of such forfeiture, expiration, termination, cash settlement or non-issuance, again be available for delivery with respect to Awards under the 2019 Plan. As of December 31, 2020, there were 2,583,565 shares of common stock available for issuance under the 2019 Plan.

In August 2021, the Company hired a new President and granted an “inducement grant” under Listing Rule 5635(c)(4) of The Nasdaq Stock Market LLC (“Nasdaq”) of 2,750,000 restricted stock units designated as “Time-Based Units” and 2,750,000 restricted stock units designated as “Performance Units” (the “August Inducement Grant”). The Time-Based Units and Performance Units were granted pursuant to certain Inducement Grant Restricted Stock Unit Agreement; accordingly, these equity awards were not counted against the shares of common stock available for issuance under the 2019 Plan.

At the 2021 annual meeting of stockholders of the Company, our stockholders approved an Offer to Exchange Eligible Options for New Restricted Stock Units (the “Exchange Offer”). The Exchange Offer allowed certain employee option holders, excluding the Company’s named executive officers, advisers, consultants, contractors, or present or past non-employee directors, to exchange some or all of their outstanding options to purchase shares of common stock that were granted before August 26, 2019, and had a per share exercise price equal to or greater than $5.01 (“Eligible Options”), for an award of restricted stock units of the Company (“New RSUs”), subject to specified conditions. In September 2021, following the expiration of the Exchange Offer, 69 eligible employees elected to exchange Eligible Options, and the Company accepted for cancellation Eligible Options to purchase an aggregate of 4,493,000 shares of common stock, representing approximately 91.5% of the total shares of common stock underlying the Eligible Options. Also, in September 2021, promptly following the expiration of the Exchange Offer, the Company granted 700,264 New RSUs in exchange for the cancellation of the tendered Eligible Options. The New RSUs vest in three equal annual installments beginning on September 29, 2022, subject to the terms and conditions of the 2019 Plan.

The following table summarizes the status of our outstanding and exercisable options and related transactions under the Plans, including the Exchange Offer, since December 31, 2020 (in thousands, except weighed average exercise price and weighted average remaining contractual life data):

	Options awards outstanding									Options awards exercisable
	Options Awards			Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)		Options Awards		Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)
As of December 31, 2020		23,782		$	4.80	$	152		5.2		19,863	$	5.06	$	117		4.6
Granted		60			1.21
Exercised		(61	)		0.40
Cancelled/Forfeited		(4,885	)		4.95
Expired		(483	)		5.59
As of September 30, 2021		18,413		$	4.40	$	21		4.2		17,228	$	4.53	$	21		3.9

The aggregate intrinsic value of options exercised during the nine months ended September 30, 2021 was less than $0.1 million.

The following table summarizes the status of our restricted stock units (“RSUs”) and related transactions, including the Exchange Offer and the August Inducement Grant since December 31, 2020 (in thousands, except weighed average grant date fair value):

	RSUs awards outstanding							RSUs awards vested and not settled
	RSUs			Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value		RSUs		Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value
As of December 31, 2020		7,061		$	1.76	$	8,544		—	$	—	$	—
Granted		11,684			1.09
Vested and settled		(2,034	)		1.17
Cancelled/Forfeited		(593	)		1.92
As of September 30, 2021		16,118		$	1.34	$	11,927		2,566	$	1.79	$	2,566

The aggregate intrinsic value of RSUs vested and settled during the nine months ended September 30, 2021 was $2.1 million.

The following table summarizes the status of our performance stock units (“PSUs”) and related transactions, including the August Inducement Grant since December 31, 2020 (in thousands, except weighed average grant date fair value):

	PSUs awards outstanding								PSUs awards vested and not settled
	PSUs				Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value		PSUs		Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value
As of December 31, 2020		2,404			$	1.08	$	2,909		—	$	—	$	—
Granted		7,337				1.05
Vested and settled		—				—
Cancelled/Forfeited		(72	)			1.07
As of September 30, 2021		9,669		⁽¹⁾	$	1.06	$	7,155		1,680	$	1.16	$	1,243

⁽¹⁾

^{The number of PSUs represents the base number of PSUs that may vest. The actual number of PSUs that will vest will be between zero and 14,901,178 depending on the Company’s achievement of certain revenue milestones over the period from 2021 through 2023 and certain earnings before interest, taxes, depreciation and amortization (EBITDA) milestones between 2021 and 2023.}

In June 2020, our stockholders approved the TherapeuticsMD, Inc. 2020 Employee Stock Purchase Plan (“ESPP”), which reserved 5,400,000 shares of our common stock for purchase by eligible employees. The ESPP permits eligible employees to purchase our common stock at a price per share which is equal to 85% of the lesser of (i) the fair market value of the shares on the offering date of the offering period or (ii) the fair market value of the shares on the purchase date. In May 2021, 150,078 shares were sold under the ESPP at an average sale price of $0.89 per share and we received proceeds of $0.1 million.

We recorded share-based compensation related to previously issued options, RSU and PSUs, as well as shares of common stock issued under the ESPP totaling $7.3 million and $3.1 million for the three months ended September 30, 2021 and 2020, respectively, and $12.8 million and $8.5 million for the nine months ended September 30, 2021 and 2020, respectively.

As of September 30, 2021, we had $22.7 million of unrecognized share-based compensation cost related to unvested options, RSUs and PSUs as well as shares issuable under the ESPP, which is included as additional paid-in capital in the accompanying consolidated balance sheets and may be adjusted for future changes in forfeitures.

The unrecognized share-based compensation cost as of September 30, 2021 is expected to be recognized as share-based compensation over a weighted average period of 2.2 years as follows (in thousands):

Year Ending December 31,
2021 (3 months)	$	3,280
2022		10,693
2023		6,206
2024		2,465
2025		6
	$	22,650

Revenue

9 Months Ended

Sep. 30, 2021

Disaggregation Of Revenue [Abstract]

Revenue

11.

Revenue

The following table provides information about disaggregated revenue by product mix and service (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
Product revenue:
ANNOVERA	$	11,807	$	6,419	$	30,112	$	10,527
IMVEXXY		8,016		6,841		24,866		18,319
BIJUVA		3,298		1,646		7,899		4,110
Prescription vitamin		1,348		2,436		4,225		7,338
Product revenue, net		24,469		17,342		67,102		40,294
License revenue		937		2,000		1,171		2,000
Total revenue, net	$	25,406	$	19,342	$	68,273	$	42,294

We have entered into a license and supply agreement (the “Knight License Agreement”), with Knight Therapeutics, Inc. (“Knight”) pursuant to which we granted Knight an exclusive license to commercialize IMVEXXY and BIJUVA in Canada and Israel. We also have entered into a licensing and supply agreement (the “Theramex License Agreement”) with Theramex HQ UK Limited (“Theramex”) pursuant to which we granted Theramex an exclusive license to commercialize IMVEXXY and BIJUVA for human use outside of the U.S., except for Canada and Israel.

For the three months and nine months ended September 30, 2021, we recorded BIJUVA sales of $0.7 million made through the Theramex License Agreement. As of September 30, 2021, no BIJUVA sales have been made through the Knight License Agreement. Additionally, as of September 30, 2021, no IMVEXXY sales have been made through either of the licensing agreements.

- Definition

The entire disclosure of revenue from contract with customer to transfer good or service and to transfer nonfinancial asset. Includes, but is not limited to, disaggregation of revenue, credit loss recognized from contract with customer, judgment and change in judgment related to contract with customer, and asset recognized from cost incurred to obtain or fulfill contract with customer. Excludes insurance and lease contracts.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
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-Name Accounting Standards Codification
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Reference 3: http://www.xbrl.org/2003/role/disclosureRef
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Reference 4: http://www.xbrl.org/2003/role/disclosureRef
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-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 12
-Subparagraph (c)
-URI http://asc.fasb.org/extlink&oid=121604090&loc=SL49130554-203045

+ Details

Income Taxes

9 Months Ended

Sep. 30, 2021

Income Tax Disclosure [Abstract]

Income Taxes

12.Income taxes

We do not expect to pay any significant federal or state income taxes as a result of (i) the losses recorded during the three and nine months ended September 30, 2021 and 2020, (ii) additional losses expected for the remainder of 2021 or losses recorded in 2020, or (iii) net operating losses carry forwards from prior years.

We recorded a full valuation allowance of the net operating losses for the three and nine months ended September 30, 2021 and 2020. Accordingly, there were no provisions for income taxes for the three and nine months ended September 30, 2021 and 2020. Additionally, as of September 30, 2021 and December 31, 2020, we maintain a full valuation allowance for all deferred tax assets.

- Definition

The entire disclosure for income taxes. Disclosures may include net deferred tax liability or asset recognized in an enterprise's statement of financial position, net change during the year in the total valuation allowance, approximate tax effect of each type of temporary difference and carryforward that gives rise to a significant portion of deferred tax liabilities and deferred tax assets, utilization of a tax carryback, and tax uncertainties information.

+ References + Details

Loss per common share

9 Months Ended

Sep. 30, 2021

Earnings Per Share [Abstract]

Loss per common share

13.Loss per common share

The following table sets forth the computation of basic and diluted loss per common share for the periods presented (in thousands, except per share amounts):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2021			2020			2021			2020
Numerator:
Net loss	$	(47,420	)	$	(32,612	)	$	(129,455	)	$	(141,437	)
Denominator:
Weighted average common shares for basic loss per common share		422,216			272,565			388,111			271,969
Effect of dilutive securities		—			—			—			—
Weighted average common shares for diluted loss per common share		422,216			272,565			388,111			271,969
Loss per common share, basic and diluted	$	(0.11	)	$	(0.12	)	$	(0.33	)	$	(0.52	)

Since we reported a net loss for the three and nine months ended September 30, 2021 and 2020, our potentially dilutive securities are deemed to be anti-dilutive, accordingly, there was no effect of dilutive securities. Therefore, our basic and diluted loss per common share and our basic and diluted weighted average common share are the same for the three and nine months ended September 30, 2021 and 2020.

The following table sets forth the outstanding securities as of the periods presented which were not included in the calculation of diluted earnings per common share during the respective three and nine months ended September 30, 2021 and 2020 (in thousands):

	As of September 30,
	2021		2020
Stock options		18,413		24,590
RSUs		16,118		6,030
PSUs		9,669		2,423
Warrants		5,127		1,783
		49,327		34,826

Related parties

9 Months Ended

Sep. 30, 2021

Related Parties

14.	Related parties

A member of our Board of Directors, J. Martin Carrol, is also a director of Catalent. From time to time, we have entered into agreements with Catalent and its affiliates in the normal course of business. Agreements with Catalent have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. For manufacturing activities, Catalent billed us $1.1 million and $0.5 million for the three months ended September 30, 2021 and 2020, respectively, and $2.6 million for the nine months ended September 30, 2021 and 2020. As of September 30, 2021 and December 31, 2020, we have estimated amounts payable to Catalent totaling less than $0.1 million and $0.3 million, respectively. In addition, we have minimum purchase requirements in place with Catalent as disclosed in Note 9, Commitments and contingencies.

A member of our Board of Directors, Karen L. Ling, was an executive vice president and chief human resources officer of American International Group, Inc. (“AIG”). From time to time, we have entered into agreements with AIG in the normal course of business. Agreements with AIG have been reviewed by independent directors of our Company, or a committee consisting of independent directors of our Company. For various insurance premiums, AIG billed us less than $0.1 million for the nine months ended September 30, 2021, and $0.1 million and $0.2 million for the three and nine months ended September 30, 2020, respectively. As of September 30, 2021 and December 31, 2020, we have no amounts payable to AIG.

Business concentrations

9 Months Ended

Sep. 30, 2021

Risks And Uncertainties [Abstract]

Business concentrations

15.	Business concentrations

We sell our products to wholesale distributors, specialty pharmacies, specialty distributors, and chain drug stores that generally sell products to retail pharmacies, hospitals, and other institutional customers.

Customers with product revenue equal to or greater than 10% of our total revenue for the periods indicated were as follows:

	Nine Months Ended September 30,
	2021	2020
Customer A	10%	14%
Customer B	16%	8%
Customer C	18%	9%
Customer D	*	8%
Customer E	12%	*
* Less than 10% of total product revenue

Customers that accounted for 10% or greater of our accounts receivable as of the periods indicated were as follows:

	September 30, 2021	December 31, 2020
Customer A	*	17%
Customer B	22%	19%
Customer C	32%	25%
Customer D	*	11%
* Balance was less than 10% of accounts receivable, gross

We rely on third parties for the manufacture and supply of our products, as well as third-party logistics providers. In instances where these parties fail to perform their obligations, we may be unable to find alternatives suppliers or satisfactorily deliver our products to our customers on time, if at all.

Vendors with product purchases equal to or greater than 10% of our total purchases for the periods indicated were as follows:

	Nine Months Ended September 30,
	2021	2020
Catalent	27%	39%
Vendor A	41%	18%
Vendor B	30%	36%
* Less than 10% of total product purchases

Vendors that accounted for 10% or greater of our accounts payable as of the periods indicated were as follows:

	September 30, 2021	December 31, 2020
Vendor E	15%	17%
Vendor F	23%	16%
Vendor G	*	10%
Vendor H	15%	*
* Balance was less than 10% of total accounts payable

Basis of presentation and summary of significant accounting policies (Policies)	9 Months Ended
	Sep. 30, 2021
Accounting Policies [Abstract]
General	General TherapeuticsMD, Inc., a Nevada corporation (the “Company”), and its consolidated subsidiaries are referred to collectively in this Quarterly Report on Form 10-Q (“10-Q Report”) as “TherapeuticsMD,” “we,” “our” and “us.” This 10-Q Report includes our trademarks, trade names and service marks, such as TherapeuticsMD^®, vitaMedMD^®, BocaGreenMD^®, vitaCare^TM, IMVEXXY^®, BIJUVA^® and ANNOVERA^®, which are protected under applicable intellectual property laws and are the property of, or licensed to, the Company. Solely for convenience, trademarks, trade names and service marks referred to in this 10-Q Report may appear without the ^®, ^TM or ^SM symbols, but such references are not intended to indicate, in any way, that we will not assert, to the fullest extent under applicable law, our rights or the right of the applicable licensor to these trademarks, trade names and service marks. We do not intend our use or display of other parties’ trademarks, trade names or service marks to imply, and such use or display should not be construed to imply a relationship with, or endorsement or sponsorship of us by, these other parties. We are a women’s healthcare company with a mission of creating and commercializing innovative products to support the lifespan of women from pregnancy prevention through menopause. At TherapeuticsMD, we combine entrepreneurial spirit, clinical expertise, and business leadership to develop and commercialize health solutions that enable new standards of care for women. Our solutions range from a patient-controlled, long-lasting contraceptive to advanced hormone therapy pharmaceutical products. We also have a portfolio of branded and generic prescription prenatal vitamins under the vitaMedMD and BocaGreenMD brands. Our portfolio of products focused on women’s health allows us to efficiently leverage our sales and marketing plan to grow our recently approved products.
Principles of consolidation	Principles of consolidation We prepared the consolidated financial statements included in this 10-Q Report following the requirements of the United States (“U.S.”) Securities and Exchange Commission (“SEC”) for interim reporting. As permitted under those rules, certain notes or other financial information that are normally required by accounting principles generally accepted in the U.S. (“U.S. GAAP”) can be condensed or omitted. Revenues, expenses, assets, liabilities, and equities can vary during each quarter of the year. Therefore, the results and trends in these interim financial statements may not be representative of those for the full year. In our opinion, all adjustments necessary for a fair statement of the financial statements, which are of a normal and recurring nature, have been made for the interim periods reported. The information included in this 10-Q Report should be read in conjunction with the consolidated financial statements and accompanying notes included in our 2020 Annual Report on Form 10-K (“2020 10-K Report”). Certain amounts in the consolidated financial statements and accompanying notes may not add due to rounding, and all percentages have been calculated using unrounded amounts.
Risks and uncertainties related to COVID-19	Risks and uncertainties related to COVID-19 We continue to be subject to risks and uncertainties in connection with the COVID-19 pandemic. The extent of the future impact of the COVID-19 pandemic on our business continues to be highly uncertain and difficult to predict. The ultimate global recovery from the pandemic will be dependent on, among other things, actions taken by governments and businesses to contain and combat the virus, including any variant strains, the speed and effectiveness of vaccine production and global distribution, as well as how quickly, and to what extent, normal economic and operating conditions can resume on a sustainable basis globally. Since the early phase of the COVID-19 pandemic, we have been using substantial virtual options to ensure business continuity. One of our subsidiaries, vitaCare^™ Prescription Services, Inc. (“vitaCare Prescription Services”), a Florida corporation, assists patients in obtaining easy and convenient access to their prescriptions for products at a pharmacy of their choice, including via home delivery pharmacy options. We have also partnered with independent community pharmacies and multiple third-party online pharmacies and telemedicine providers that focus on contraception or menopause which provide patients real-time access to both diagnosis and treatment. We continue to support prescribers’ needs with samples and product materials through our sales force. If access is restricted, we have mailing options in place for these materials. We also have business continuity plans and infrastructure in place that allows for live virtual e-detailing of our products. As part of our response to the COVID-19 pandemic, we implemented measures to reduce marketing expenses for 2020. We also implemented cost saving measures in 2020, which included negotiating lower fees or suspending services from third party vendors; implementing a company-wide hiring restriction; delaying or cancelling non-critical information technology projects; and eliminating non-essential travel, entertainment, meeting, and event expenses. In addition, we are planning to implement a significant cost savings initiative that is designed to reduce our annual costs in 2022 by at least $40.0 million. This figure does not include cost savings from, or the costs associated with the sale of an interest in vitaCare Prescription Services, which annualized cost savings are estimated at approximately $20.0 million. The full impact of the COVID-19 pandemic continues to evolve. However, we remain committed to the execution of our corporate goals, despite the ongoing COVID-19 pandemic, as demonstrated in part by the increase in product revenue throughout 2021. As of the date of issuance of these consolidated financial statements, the future extent to which the COVID-19 pandemic may continue to materially impact our financial condition, liquidity, or results of operations remains uncertain. We are continuing to assess the effect of the COVID-19 pandemic on our operations by monitoring the spread of COVID-19 and the various actions implemented to combat the pandemic throughout the world. Even after the COVID-19 pandemic has subsided, we may continue to experience adverse impacts to our business as a result of any economic recession or depression that has occurred or may occur in the future. While we currently believe that our COVID-19 contingency plan has the ability to mitigate many of the negative effects of the COVID-19 pandemic on our business, the severity of the impact of the COVID-19 pandemic on our business will depend on a number of factors, including, but not limited to, the duration and severity of the pandemic, the duration of “social distancing” orders, the ability of our sales force to access healthcare providers to promote our products, increases in unemployment, which could reduce access to commercial health insurance for our patients, thus limiting payer coverage for our products, and the impact of the pandemic on our global supply chain, all of which remain uncertain. Our future results of operations and liquidity could be materially adversely affected by delays in payments of outstanding receivable amounts beyond normal payment terms, supply chain disruptions, uncertain demand, and the impact of any initiatives or programs that we may undertake to address financial and operations challenges that we may face.
Going Concern	Going Concern As of the filing date of this Quarterly Report on Form 10-Q, our cash balance was above the $60.0 million balance as required by the Financing Agreement described below in Note 8. Based on our current projections, we will need to raise additional capital to remain in compliance with this minimum cash balance covenant for the next twelve months from the issuance of these financial statements. To address our projected capital needs, we are pursuing various equity financing and other alternatives including the sale of an interest in vitaCare Prescription Services for which we commenced a sale process. The equity financing alternatives may include the private placement of equity, equity-linked, or other similar instruments or obligations with one or more investors, lenders, or other institutional counterparties or an underwritten public equity or equity-linked securities offering. Our ability to sell equity securities may be limited by market conditions. To the extent that we raise additional capital through the sale of such securities, the ownership interests of our existing stockholders will be diluted, and the terms of these new securities may include liquidation or other preferences that adversely affect the rights of our existing stockholders. Along with considering additional financings, we have reviewed numerous potential scenarios in connection with steps that we may take to reduce our operating expenses. Based on our analysis, we believe that our existing cash reserves along with potential proceeds from the sale of certain non-core assets of the Company and proceeds from potential future financings, if available to us, would be sufficient to meet our cash needs arising in the ordinary course of business for the next twelve months from the date of this Quarterly Report on Form 10-Q. If we are unsuccessful with future financings and if the successful commercialization of IMVEXXY, BIJUVA, or ANNOVERA is delayed, or the continued impact of the COVID-19 pandemic or issues in our supply chains related to our third party contract manufacturers on our business is worse than we anticipate, our existing cash reserves would be insufficient to maintain compliance with the Financing Agreement covenants or satisfy our liquidity requirements until we are able to successfully commercialize IMVEXXY, BIJUVA, and ANNOVERA. See also Note 3- Inventory for additional information regarding risks associated with our contract manufacturers, particularly for ANNOVERA. The presence of these projected factors in conjunction with the uncertainty of the capital markets raises substantial doubt about the Company's ability to continue as a going concern for the next twelve months from the issuance of these financial statements. Additionally, if circumstances were to require our independent registered public accounting firm to include a going concern uncertainty in their report on our annual consolidated financial statements, such matter would also take us out of compliance with certain of the Financing Agreement covenants. If we are unable to achieve any of the total minimum net revenue requirements or otherwise comply with any other covenant of the Financing Agreement, all or a portion of our obligations under the Financing Agreement may be declared immediately due and payable, which would have an adverse effect on our business, results of operations and financial condition. The accompanying unaudited consolidated financial statements do not include any adjustments that might be necessary if the Company is unable to continue as a going concern.
Significant accounting policies	Significant accounting policies The significant accounting policies we use for quarterly financial reporting are disclosed in Note 2, Summary of Significant Accounting Policies of the accompanying notes to the consolidated financial statements included in our 2020 10-K Report, and in the section below.
Accounting standards issued but not yet adopted	Accounting standards issued but not yet adopted There have been no recently issued accounting standards not yet adopted by us which are expected, upon adoption, to have a material impact on our consolidated financial statements or processes.
Reclassification	Reclassification Certain amounts, including type of operating expenses, reported in prior periods in the financial statements have been reclassified to conform to the current period’s presentation.

Accounts receivable (Tables)

9 Months Ended

Sep. 30, 2021

Receivables [Abstract]

Summary of accounts receivable allowance for credit losses

The following sets forth activities in our allowance for credit losses (in thousands):

	Total
Balance as of January 1, 2021	$	1,118
Charges to provision for credit losses		540
Write-off of uncollectible receivables		(307	)
Balance as of September 30, 2021	$	1,351

Inventory (Tables)

9 Months Ended

Sep. 30, 2021

Inventory Disclosure [Abstract]

Summary of Inventory

Our inventory consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Raw materials	$	3,487	$	4,423
Work in process		688		220
Finished products		3,187		3,350
Inventory	$	7,362	$	7,993

Prepaid and other current assets (Tables)

9 Months Ended

Sep. 30, 2021

Prepaid Expense And Other Assets Current [Abstract]

Schedule of prepaid and other current assets

Our prepaid and other current assets consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Insurance	$	3,801	$	2,568
Paragraph IV legal proceeding costs		2,858		—
Other		3,715		4,975
Prepaid and other current assets	$	10,374	$	7,543

Fixed assets (Tables)

9 Months Ended

Sep. 30, 2021

Property Plant And Equipment [Abstract]

Summary of Fixed Assets, Net

Our fixed assets, net consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Furniture and fixtures	$	1,407	$	1,407
Computer and office equipment		1,855		1,784
Computer software		375		412
Leasehold improvements		80		80
Fixed assets		3,717		3,683
Less: accumulated depreciation and amortization		2,329		1,741
Fixed assets, net	$	1,388	$	1,942

Licensed rights and other intangible assets (Tables)

9 Months Ended

Sep. 30, 2021

Goodwill And Intangible Assets Disclosure [Abstract]

Summary of Information about License Rights and Other Intangible Assets, Net

The following provides information about our license rights and other intangible assets, net (in thousands):

	September 30, 2021						December 31, 2020
	Gross						Gross
	Carrying		Accumulated				Carrying		Accumulated
	Amount		Amortization		Net		Amount		Amortization		Net
Licensed rights and intangible assets subject to amortization:
License rights	$	40,000	$	6,070	$	33,930	$	40,000	$	3,803	$	36,197
Hormone therapy drug patents		4,732		985		3,747		4,045		749		3,296
Hormone therapy drug patents applied and pending approval		1,596		—		1,596		1,629		—		1,629
License rights and other intangible assets subject to amortization		46,328		7,055		39,273		45,674		4,552		41,122
Intangible assets not subject to amortization:
Trademarks/trade name rights		344		—		344		323		—		323
License rights and other intangible assets, net	$	46,672	$	7,055	$	39,617	$	45,997	$	4,552	$	41,445

Accrued expenses and other current liabilities (Tables)

9 Months Ended

Sep. 30, 2021

Payables And Accruals [Abstract]

Schedule of Other Accrued Expenses and Other Current Liabilities

Other accrued expenses and other current liabilities consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Payroll and related costs	$	14,346	$	11,179
Rebates		15,421		11,011
Sales returns and coupons		3,200		7,057
Sales and marketing		6,223		228
Wholesale distributor fees		4,626		2,632
Professional fees		2,477		925
Other accrued expenses and current liabilities		5,381		5,138
Accrued expenses and other current liabilities	$	51,674	$	38,170

Debt (Tables)

9 Months Ended

Sep. 30, 2021

Debt Disclosure [Abstract]

Schedule of Debt

Our debt consisted of the following (in thousands):

	September 30, 2021		December 31, 2020
Financing Agreement	$	200,000	$	250,000
Less: deferred financing fees		13,262		12,302
Debt, net		186,738		237,698
Current maturities of long-term debt		15,000		—
Long-term debt	$	171,738	$	237,698

Summary of Future Principal Payments under Financing Agreement

Our future principal payments under the Financing Agreement are as follows (in thousands), excluding the prepayment fees described above:

Due on
	March 31,		June 30,		September 30,		December 31,		Total
2022	$	5,000	$	5,000	$	5,000	$	10,000	$	25,000
2023		10,000		41,250		41,250		41,250		133,750
2024		41,250		—		—		—		41,250
									$	200,000

The estimated future amortization of our deferred financing fees is as follows (in thousands):

Year Ending December 31,
2021 (3 months)	$	1,532
2022		6,346
2023		4,990
2024		394
	$	13,262

Summary of Interest Expense and Other Financing Costs

Interest expense and other financing costs consisted of the following (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
Interest expense	$	5,391	$	6,727	$	17,175	$	19,324
Interest prepayment fees		650		—		4,008		—
Financing fees amortization		1,477		953		4,158		1,645
Interest expense and other financing costs	$	7,518	$	7,680	$	25,341	$	20,969

- Definition

Tabular disclosure of long-debt instruments or arrangements, including identification, terms, features, collateral requirements and other information necessary to a fair presentation. These are debt arrangements that originally required repayment more than twelve months after issuance or greater than the normal operating cycle of the entity, if longer.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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-Paragraph 1
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+ Details

Stockholders’ Equity (Deficit) (Tables)

9 Months Ended

Sep. 30, 2021

Summary of our Outstanding and Exercisable Warrants and Related Transactions

	Warrants outstanding and exercisable
	Warrants			Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)
As of December 31, 2020		6,535		$	1.55	$	1,041		7.3
Exercised		(1,163	)		0.31
Expired		(245	)		4.80
As of September 30, 2021		5,127		$	1.52	$	-		8.6

Summary of Stock Option Activity

	Options awards outstanding									Options awards exercisable
	Options Awards			Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)		Options Awards		Weighted Average Exercise Price		Aggregate Intrinsic Value		Weighted Average Remaining Contractual Life (in Years)
As of December 31, 2020		23,782		$	4.80	$	152		5.2		19,863	$	5.06	$	117		4.6
Granted		60			1.21
Exercised		(61	)		0.40
Cancelled/Forfeited		(4,885	)		4.95
Expired		(483	)		5.59
As of September 30, 2021		18,413		$	4.40	$	21		4.2		17,228	$	4.53	$	21		3.9

Summary of Unrecognized Share Based Compensation Cost Expected to be Recognized

The unrecognized share-based compensation cost as of September 30, 2021 is expected to be recognized as share-based compensation over a weighted average period of 2.2 years as follows (in thousands):

Year Ending December 31,
2021 (3 months)	$	3,280
2022		10,693
2023		6,206
2024		2,465
2025		6
	$	22,650

Restricted Stock Units [Member]

Schedule of RSUs and PSUs

	RSUs awards outstanding							RSUs awards vested and not settled
	RSUs			Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value		RSUs		Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value
As of December 31, 2020		7,061		$	1.76	$	8,544		—	$	—	$	—
Granted		11,684			1.09
Vested and settled		(2,034	)		1.17
Cancelled/Forfeited		(593	)		1.92
As of September 30, 2021		16,118		$	1.34	$	11,927		2,566	$	1.79	$	2,566

Performance Shares Unit [Member]

Schedule of RSUs and PSUs

	PSUs awards outstanding								PSUs awards vested and not settled
	PSUs				Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value		PSUs		Weighted Average Grant Date Fair Value		Aggregate Intrinsic Value
As of December 31, 2020		2,404			$	1.08	$	2,909		—	$	—	$	—
Granted		7,337				1.05
Vested and settled		—				—
Cancelled/Forfeited		(72	)			1.07
As of September 30, 2021		9,669		⁽¹⁾	$	1.06	$	7,155		1,680	$	1.16	$	1,243

⁽¹⁾

Revenue (Tables)

9 Months Ended

Sep. 30, 2021

Disaggregation Of Revenue [Abstract]

Summary of information about disaggregated revenue by product mix

The following table provides information about disaggregated revenue by product mix and service (in thousands):

	Three Months Ended September 30,				Nine Months Ended September 30,
	2021		2020		2021		2020
Product revenue:
ANNOVERA	$	11,807	$	6,419	$	30,112	$	10,527
IMVEXXY		8,016		6,841		24,866		18,319
BIJUVA		3,298		1,646		7,899		4,110
Prescription vitamin		1,348		2,436		4,225		7,338
Product revenue, net		24,469		17,342		67,102		40,294
License revenue		937		2,000		1,171		2,000
Total revenue, net	$	25,406	$	19,342	$	68,273	$	42,294

Loss per common share (Tables)

9 Months Ended

Sep. 30, 2021

Earnings Per Share [Abstract]

Summary of computation of basic and diluted loss per common share

The following table sets forth the computation of basic and diluted loss per common share for the periods presented (in thousands, except per share amounts):

	Three Months Ended September 30,						Nine Months Ended September 30,
	2021			2020			2021			2020
Numerator:
Net loss	$	(47,420	)	$	(32,612	)	$	(129,455	)	$	(141,437	)
Denominator:
Weighted average common shares for basic loss per common share		422,216			272,565			388,111			271,969
Effect of dilutive securities		—			—			—			—
Weighted average common shares for diluted loss per common share		422,216			272,565			388,111			271,969
Loss per common share, basic and diluted	$	(0.11	)	$	(0.12	)	$	(0.33	)	$	(0.52	)

Schedule of antidilutive securities excluded from computation of earnings per share

	As of September 30,
	2021		2020
Stock options		18,413		24,590
RSUs		16,118		6,030
PSUs		9,669		2,423
Warrants		5,127		1,783
		49,327		34,826

Business Concentrations (Tables)

9 Months Ended

Sep. 30, 2021

Disclosure of Revenue and Purchases [Line Items]

Summary of Customers with Product Revenue and Accounts Receivable

Customers with product revenue equal to or greater than 10% of our total revenue for the periods indicated were as follows:

	Nine Months Ended September 30,
	2021	2020
Customer A	10%	14%
Customer B	16%	8%
Customer C	18%	9%
Customer D	*	8%
Customer E	12%	*
* Less than 10% of total product revenue

Summary of Vendors with Product Purchases and Accounts Payable

Vendors with product purchases equal to or greater than 10% of our total purchases for the periods indicated were as follows:

	Nine Months Ended September 30,
	2021	2020
Catalent	27%	39%
Vendor A	41%	18%
Vendor B	30%	36%
* Less than 10% of total product purchases

Accounts Receivable [Member]

Disclosure of Revenue and Purchases [Line Items]

Summary of Customers with Product Revenue and Accounts Receivable

Customers that accounted for 10% or greater of our accounts receivable as of the periods indicated were as follows:

	September 30, 2021	December 31, 2020
Customer A	*	17%
Customer B	22%	19%
Customer C	32%	25%
Customer D	*	11%
* Balance was less than 10% of accounts receivable, gross

Accounts Payable [Member]

Disclosure of Revenue and Purchases [Line Items]

Summary of Vendors with Product Purchases and Accounts Payable

Vendors that accounted for 10% or greater of our accounts payable as of the periods indicated were as follows:

	September 30, 2021	December 31, 2020
Vendor E	15%	17%
Vendor F	23%	16%
Vendor G	*	10%
Vendor H	15%	*
* Balance was less than 10% of total accounts payable

Basis of presentation and summary of significant accounting policies - Additional Information (Details)	Sep. 30, 2021 USD ($)
Financing Agreement [Member] \| Forecasted Debt Covenant Compliance [Member]
Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items]
Minimum cash balance requirement under credit agreement	$ 60,000,000.0
VitaCare Prescription Services [Member] \| COVID-19 [Member]
Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items]
Cost savings initiative to reduce annual costs	20,000,000.0
Minimum [Member] \| COVID-19 [Member]
Basis Of Presentation And Summary Of Significant Accounting Policies [Line Items]
Cost savings initiative to reduce annual costs	$ 40,000,000.0

Accounts receivable - Summary Of Accounts Receivable Allowance For Credit Losses (Details) - USD ($) $ in Thousands	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Credit Loss Abstract
Beginning balance	$ 1,118
Charges to provision for credit losses	540	$ (47)
Write-off of uncollectible receivables	(307)
Ending Balance	$ 1,351

Inventory - Summary of Inventory (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Inventory Disclosure [Abstract]
Raw materials	$ 3,487	$ 4,423
Work in process	688	220
Finished products	3,187	3,350
Inventory	$ 7,362	$ 7,993

Prepaid and other current assets - Schedule of prepaid and other current assets consisted of the following (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Prepaid Expense And Other Assets Current [Abstract]
Insurance	$ 3,801	$ 2,568
Paragraph IV legal proceeding costs	2,858
Other	3,715	4,975
Prepaid and other current assets	$ 10,374	$ 7,543

Fixed assets - Summary of Fixed Assets, Net (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Property Plant And Equipment [Line Items]
Fixed assets	$ 3,717	$ 3,683
Less: accumulated depreciation and amortization	2,329	1,741
Fixed assets, net	1,388	1,942
Furniture and fixtures [Member]
Property Plant And Equipment [Line Items]
Fixed assets	1,407	1,407
Computer and office equipment [Member]
Property Plant And Equipment [Line Items]
Fixed assets	1,855	1,784
Computer software [Member]
Property Plant And Equipment [Line Items]
Fixed assets	375	412
Leasehold improvements [Member]
Property Plant And Equipment [Line Items]
Fixed assets	$ 80	$ 80

Fixed assets - Additional Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Property Plant And Equipment [Abstract]
Depreciation	$ 0.2	$ 0.2	$ 0.6	$ 0.6

Licensed rights and other intangible assets - Summary of Information about License Rights and Other Intangible Assets, Net (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	$ 46,328	$ 45,674
Finite-Lived Intangible Assets, Accumulated Amortization	7,055	4,552
Finite-Lived Intangible Assets, Net	39,273	41,122
License Rights and Intangible Assets, Net, Gross Carrying Amount (Excluding Goodwill)	46,672	45,997
License rights and other intangible assets, net	39,617	41,445
Trademarks/trade name rights [Member]
Finite-Lived Intangible Assets [Line Items]
Indefinite-Lived Intangible Assets, Gross Carrying Amount and Net	344	323
License rights [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	40,000	40,000
Finite-Lived Intangible Assets, Accumulated Amortization	6,070	3,803
Finite-Lived Intangible Assets, Net	33,930	36,197
Hormone therapy drug patents [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	4,732	4,045
Finite-Lived Intangible Assets, Accumulated Amortization	985	749
Finite-Lived Intangible Assets, Net	3,747	3,296
Hormone therapy drug candidate patents - applied and pending [Member]
Finite-Lived Intangible Assets [Line Items]
Finite-Lived Intangible Assets, Gross Carrying Amount	1,596	1,629
Finite-Lived Intangible Assets, Net	$ 1,596	$ 1,629

Licensed rights and other intangible assets - Additional Information (Details)	3 Months Ended		9 Months Ended
	Sep. 30, 2021 USD ($) Patent	Sep. 30, 2020 USD ($)	Sep. 30, 2021 USD ($) Patent	Sep. 30, 2020 USD ($)	Dec. 31, 2020 Patent
Finite-Lived Intangible Assets [Line Items]
Number of issued patents \| Patent	87		87		77
Write off of patent and trademark cost				$ 584,509
License rights [Member]
Finite-Lived Intangible Assets [Line Items]
Amortization of intangible assets	$ 800,000	$ 800,000	$ 2,300,000	2,300,000
Domestic US Patents [Member]
Finite-Lived Intangible Assets [Line Items]
Number of issued patents \| Patent	46		46		38
Patents [Member]
Finite-Lived Intangible Assets [Line Items]
Amortization of intangible assets	$ 100,000	$ 100,000	$ 200,000	$ 200,000

Accrued expenses and other current liabilities - Schedule of Other Accrued Expenses and Other Current Liabilities (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Payables And Accruals [Abstract]
Payroll and related costs	$ 14,346	$ 11,179
Rebates	15,421	11,011
Sales returns and coupons	3,200	7,057
Sales and marketing	6,223	228
Wholesale distributor fees	4,626	2,632
Professional fees	2,477	925
Other accrued expenses and current liabilities	5,381	5,138
Accrued expenses and other current liabilities	$ 51,674	$ 38,170

Debt - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Mar. 31, 2021	Sep. 30, 2021	Sep. 30, 2020
Debt Instrument [Line Items]
Debt financing fee paid		$ 5,118	$ 1,250
Repayments of debt		50,000
Deferred offering costs		5,000
Repayment on March 31, 2022 [Member]
Debt Instrument [Line Items]
Prepayment fee percentage	30.00%
Repayment on March 31, 2022 [Member] \| Financing Agreement Amendment No 8 [Member]
Debt Instrument [Line Items]
Prepayment fee percentage	5.00%
Additional principal repayment	$ 5,000
Repayment on April1, 2022 through March 31, 2023 [Member]
Debt Instrument [Line Items]
Prepayment fee percentage	5.00%
Repayments from April 1, 2023 through March 31, 2024 [Member]
Debt Instrument [Line Items]
Prepayment fee percentage	3.00%
Imvexxy Bijuva and Annovera [Member]
Debt Instrument [Line Items]
Repayments of debt	$ 50,000
Prepayment fee percentage	5.00%
Financing Agreement Amendment 7 [Member] \| Long-term Debt [Member]
Debt Instrument [Line Items]
Debt financing fee paid		5,000
Financing Agreement [Member] \| Forecasted Debt Covenant Compliance [Member]
Debt Instrument [Line Items]
Minimum cash balance requirement under credit agreement		$ 60,000

Debt - Schedule of Debt (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Debt Instrument [Line Items]
Less: deferred financing fees	$ 13,262	$ 12,302
Debt, net	186,738	237,698
Current maturities of long-term debt	15,000
Long-term Debt	171,738	237,698
Financing Agreement [Member]
Debt Instrument [Line Items]
Financing Agreement	$ 200,000	$ 250,000

Debt - Summary of Future Principal Payments under Financing Agreement Excluding Prepayment Fees (Details) - USD ($) $ in Thousands	Dec. 31, 2021	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Dec. 31, 2020
Debt Instrument [Line Items]
2022		$ 5,000	$ 5,000	$ 5,000
2023		41,250	$ 41,250	10,000
2024				$ 41,250
Debt, net		$ 186,738			$ 237,698
Forecast
Debt Instrument [Line Items]
2022	$ 10,000
2023	41,250
2022	25,000
2023	133,750
2024	41,250
Debt, net	$ 200,000

Debt - Summary of Interest Expense and Other Financing Costs (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Debt Disclosure [Abstract]
Interest expense	$ 5,391	$ 6,727	$ 17,175	$ 19,324
Interest prepayment fees	650		4,008
Debt financing fees	1,477	953	4,158	1,645
Interest expense and other financing costs	$ 7,518	$ 7,680	$ 25,341	$ 20,969

Debt - Summary of Future Estimated Amortization of Deferred Financing Fees (Details) - USD ($) $ in Thousands	Sep. 30, 2021	Dec. 31, 2020
Estimated Future Amortization Of Deferred Financing Fee Disclosure [Line Items]
Deferred financing fees	$ 13,262	$ 12,302
2021
Estimated Future Amortization Of Deferred Financing Fee Disclosure [Line Items]
Deferred financing fees	1,532
2022
Estimated Future Amortization Of Deferred Financing Fee Disclosure [Line Items]
Deferred financing fees	6,346
2023
Estimated Future Amortization Of Deferred Financing Fee Disclosure [Line Items]
Deferred financing fees	4,990
2024
Estimated Future Amortization Of Deferred Financing Fee Disclosure [Line Items]
Deferred financing fees	$ 394

Commitments and Contingencies - Additional Information (Details) $ in Millions	9 Months Ended
	Sep. 30, 2021 USD ($)
Prepaid Expenses and Other Current Assets [Member] \| Paragraph Four Certification Notice Letter [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Legal proceeding costs	$ 2.9
BIJUVA [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Minimum supply commitment fee percentage payable	50.00%
IMVEXXY [Member]
Recorded Unconditional Purchase Obligation [Line Items]
Minimum supply commitment fee percentage payable	60.00%

Stockholders' Equity (Deficit) - Common Stock and Warrants - Additional Information (Details) - USD ($) $ / shares in Units, $ in Millions		1 Months Ended			3 Months Ended			9 Months Ended
	Feb. 08, 2021	Mar. 31, 2021	Feb. 28, 2021	Nov. 30, 2020	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2021
Common Stock [Member]
Class Of Stock [Line Items]
Proceeds from stock plans			$ 96.6
Shares issued for sale of common stock, net of cost, shares			59,459,460		28,770,000	125,000	92,870,000
Shares issued, price per share			$ 1.85
Warrant [Member]
Class Of Stock [Line Items]
Aggregate intrinsic value of options exercised								$ 1.1
2020 ATM Program [Member] \| Common Stock [Member]
Class Of Stock [Line Items]
Public offering of common stock authorized for sale				$ 50.0
Sale of stock, number of shares issued in transaction	28,600,689
Proceeds from stock plans	$ 48.1
2021 ATM Program [Member] \| Common Stock [Member]
Class Of Stock [Line Items]
Public offering of common stock authorized for sale		$ 100.0
Percentage of commission rate gross sales price		3.00%		3.00%			3.00%
Sale of stock, number of shares issued in transaction								33,705,315
Sale of stock, price Per share	$ 1.75				$ 1.21			$ 1.21
Proceeds from stock plans								$ 38.8

Stockholders' Equity (Deficit) - Summary of our Outstanding and Exercisable Warrants and Related Transactions (Details) - Warrant [Member] - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
Class Of Warrant Or Right [Line Items]
Beginning balance, Warrants	6,535
Exercised, Warrants	(1,163)
Expired, Warrants	(245)
Ending balance, Warrants	5,127	6,535
Beginning balance, Weighted Average Exercise Price	$ 1.55
Exercised, Weighted Average Exercise Price	0.31
Expired, Weighted Average Exercise Price	4.80
Ending balance, Weighted Average Exercise Price	$ 1.52	$ 1.55
Warrants, Aggregate Intrinsic Value		$ 1,041
Warrants, Weighted Average Remaining Contractual Life (in Years)	8 years 7 months 6 days	7 years 3 months 18 days

Stockholders' Equity (Deficit) - Share-based Compensation Payment Plans - Additional Information (Details)	1 Months Ended				3 Months Ended		9 Months Ended
	Sep. 30, 2021 USD ($) Employee Installment $ / shares shares	Aug. 31, 2021 shares	May 31, 2021 USD ($) $ / shares shares	Jun. 30, 2020 shares	Sep. 30, 2021 USD ($) shares	Sep. 30, 2020 USD ($)	Sep. 30, 2021 USD ($) shares	Sep. 30, 2020 USD ($)	May 27, 2021 shares	Dec. 31, 2020 shares
Class Of Stock [Line Items]
Exercise price per share \| $ / shares	$ 5.01
Eligible Employees who elected to exchange Eligible Options \| Employee	69
Options granted to purchase an aggregate shares of common stock	4,493,000				4,493,000		4,493,000
Percentage of shares of common stock underlying eligible options	91.50%				91.50%		91.50%
Number of annual installments vest \| Installment	3
Common Stock, Shares, Issued	424,879,000				424,879,000		424,879,000			299,765,000
Share-based payment arrangement, expense \| $					$ 7,300,000	$ 3,100,000	$ 12,800,000	$ 8,500,000
Total unrecognized share based compensation \| $	$ 22,700,000				$ 22,700,000		$ 22,700,000
Share-based compensation over a weighted average period							2 years 2 months 12 days
Restricted Stock Units [Member]
Class Of Stock [Line Items]
Share based compensation arrangement by share based payment award, grants in period in exchange for cancellation of tendered eligible options	700,264
Aggregate intrinsic value of vested and settled \| $							$ 2,100,000
Share-based Payment Arrangement, Option [Member] \| Maximum [Member]
Class Of Stock [Line Items]
Aggregate intrinsic value of options exercised \| $							$ 100,000
2019 Stock Incentive Plan [Member]
Class Of Stock [Line Items]
Number of shares common stock available									22,475,000
2019 Stock Incentive Plan [Member] \| Restricted Stock Units [Member] \| Time-Based Units [Member]
Class Of Stock [Line Items]
Share-based compensation arrangement by share-based payment award, grants in period		2,750,000
2019 Stock Incentive Plan [Member] \| Restricted Stock Units [Member] \| Performance Units [Member]
Class Of Stock [Line Items]
Share-based compensation arrangement by share-based payment award, grants in period		2,750,000
Plan 2019 [Member]
Class Of Stock [Line Items]
Share-based compensation arrangement by share-based payment award, number of shares authorized	10,182,803				10,182,803		10,182,803			2,583,565
Employee Stock Purchase Plan [Member]
Class Of Stock [Line Items]
Number of shares common stock available				5,400,000
Common Stock, Shares, Issued			150,078
Eligible employees to purchase common stock price per share equal to percentage				85.00%
Sale of stock, price Per share \| $ / shares			$ 0.89
Proceeds from stock plans \| $			$ 100,000

Stockholders' Equity (Deficit) - Summary of Stock Option Activity (Details) $ / shares in Units, shares in Thousands, $ in Thousands	9 Months Ended	12 Months Ended
	Sep. 30, 2021 USD ($) $ / shares shares	Dec. 31, 2020 USD ($) $ / shares shares
Equity [Abstract]
Options awards outstanding, Beginning balance \| shares	23,782
Options awards outstanding, Granted \| shares	60
Options awards outstanding, Exercised \| shares	(61)
Options awards outstanding, Cancelled/Forfeited \| shares	(4,885)
Options awards outstanding, Expired \| shares	(483)
Options awards outstanding, Ending balance \| shares	18,413	23,782
Options award outstanding, weighted average exercise price, Beginning balance \| $ / shares	$ 4.80
Options award outstanding, weighted average exercise price, Granted \| $ / shares	1.21
Options award outstanding, weighted average exercise price, Exercised \| $ / shares	0.40
Options award outstanding, weighted average exercise price, Cancelled/Forfeited \| $ / shares	4.95
Options award outstanding, weighted average exercise price, Expired \| $ / shares	5.59
Options award outstanding, weighted average exercise price, Ending balance \| $ / shares	$ 4.40	$ 4.80
Options award outstanding, aggregate intrinsic value \| $	$ 21	$ 152
Options award outstanding, weighted average remaining contractual life	4 years 2 months 12 days	5 years 2 months 12 days
Options award exercisable \| shares	17,228	19,863
Options award exercisable, weighted average exercise price \| $ / shares	$ 4.53	$ 5.06
Options award exercisable, aggregate intrinsic value \| $	$ 21	$ 117
Options award exercisable, weighted average remaining contractual life	3 years 10 months 24 days	4 years 7 months 6 days

Stockholders' Equity (Deficit) - Schedule of Restricted Stock Units (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	9 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
RSU Awards Outstanding [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Beginning balance, number of shares	7,061
Share-based compensation arrangement by share-based payment award, grants in period	11,684
Vested/Released, number of shares	(2,034)
Forfeited, number of shares	(593)
Ending balance, number of shares	16,118
Beginning balance, weighted average grant date fair value	$ 1.76
Granted, weighted average grant date fair value	1.09
Vested/Released, weighted average grant date fair value	1.17
Forfeited, weighted average grant date fair value	1.92
Ending balance, weighted average grant date fair value	$ 1.34
Aggregate intrinsic value	$ 11,927	$ 8,544
RSU Awards Vested and Not Settled [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Ending balance, number of shares	2,566
Ending balance, weighted average grant date fair value	$ 1.79
Aggregate intrinsic value	$ 2,566

Stockholders' Equity (Deficit) - Schedule of Performance Stock Units (Details) - USD ($)
$ / shares in Units, shares in Thousands, $ in Thousands

9 Months Ended

Sep. 30, 2021

Dec. 31, 2020

PSUs Awards Outstanding [Member]

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Beginning balance, number of shares

2,404

Share-based compensation arrangement by share-based payment award, grants in period

7,337

Forfeited, number of shares

(72)

Ending balance, number of shares

^[1]

9,669

Beginning balance, weighted average grant date fair value

$ 1.08

Granted, weighted average grant date fair value

1.05

Forfeited, weighted average grant date fair value

1.07

Ending balance, weighted average grant date fair value

$ 1.06

Aggregate intrinsic value

$ 7,155

$ 2,909

PSUs Awards Vested and Not Settled [Member]

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Ending balance, number of shares

1,680

Ending balance, weighted average grant date fair value

$ 1.16

Aggregate intrinsic value

$ 1,243

[1]

The number of PSUs represents the base number of PSUs that may vest. The actual number of PSUs that will vest will be between zero and 14,901,178 depending on the Company’s achievement of certain revenue milestones over the period from 2021 through 2023 and certain earnings before interest, taxes, depreciation and amortization (EBITDA) milestones between 2021 and 2023.

Stockholders' Equity (Deficit) - Schedule of Performance Stock Units (Parenthetical) (Details) - Performance Shares Unit [Member]	Sep. 30, 2021 shares
Minimum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares expected to vest	0
Maximum [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Number of shares expected to vest	14,901,178

Stockholders' Equity (Deficit) - Summary of Unrecognized Share Based Compensation Cost Expected to be Recognized (Details) $ in Thousands	Sep. 30, 2021 USD ($)
Equity [Abstract]
2021 (3 months)	$ 3,280
2022	10,693
2023	6,206
2024	2,465
2025	6
Total	$ 22,650

Revenue - Summary of information about disaggregated revenue by product mix (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 25,406	$ 19,342	$ 68,273	$ 42,294
ANNOVERA [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	11,807	6,419	30,112	10,527
IMVEXXY [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	8,016	6,841	24,866	18,319
BIJUVA [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	3,298	1,646	7,899	4,110
Prescription Vitamins [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	1,348	2,436	4,225	7,338
Product [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	24,469	17,342	67,102	40,294
License [Member]
Product revenue:
Revenue from Contract with Customer, Including Assessed Tax	$ 937	$ 2,000	$ 1,171	$ 2,000

- Definition

Amount, including tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value-added and excise.

+ References

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 41
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e9038-108599

Reference 2: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
-SubTopic 10
-Section 50
-Paragraph 5
-URI http://asc.fasb.org/extlink&oid=121604090&loc=SL49130545-203045

Reference 3: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 32
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8933-108599

Reference 4: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 32
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8933-108599

Reference 5: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8906-108599

Reference 6: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8736-108599

Reference 7: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Subparagraph (a)
-URI http://asc.fasb.org/extlink&oid=120311839&loc=d3e8736-108599

Reference 8: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 606
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+ Details

Revenue - Additional Information (Details) - USD ($)	3 Months Ended		9 Months Ended
Revenue - Additional Information (Details) - USD ($)	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Disaggregation of Revenue [Line Items]
Sales	$ 25,406,000	$ 19,342,000	$ 68,273,000	$ 42,294,000
BIJUVA [Member]
Disaggregation of Revenue [Line Items]
Sales	3,298,000	1,646,000	7,899,000	4,110,000
IMVEXXY [Member]
Disaggregation of Revenue [Line Items]
Sales	8,016,000	$ 6,841,000	24,866,000	$ 18,319,000
Theramex License Agreement [Member] \| BIJUVA [Member]
Disaggregation of Revenue [Line Items]
Sales	700,000		700,000
Knight License Agreement [Member] \| BIJUVA [Member]
Disaggregation of Revenue [Line Items]
Sales	0		0
Theramex and Knight License Agreement [Member[ \| IMVEXXY [Member]
Disaggregation of Revenue [Line Items]
Sales	$ 0		$ 0

- Definition

+ References

+ Details

Income Taxes - Additional Information (Details) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020
Income Tax Disclosure [Abstract]
Provision for income taxes	$ 0	$ 0	$ 0	$ 0

- Definition

Amount of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

+ References + Details

Loss per common share - Summary of computation of basic and diluted loss per common share (Details) - USD ($) $ / shares in Units, shares in Thousands, $ in Thousands	3 Months Ended						9 Months Ended
	Sep. 30, 2021	Jun. 30, 2021	Mar. 31, 2021	Sep. 30, 2020	Jun. 30, 2020	Mar. 31, 2020	Sep. 30, 2021	Sep. 30, 2020
Numerator:
Net loss	$ (47,420)	$ (42,652)	$ (39,383)	$ (32,612)	$ (51,976)	$ (56,849)	$ (129,455)	$ (141,437)
Denominator:
Weighted average common shares for basic loss per common share	422,216			272,565			388,111	271,969
Effect of dilutive securities	0			0			0	0
Weighted average common shares for diluted loss per common share	422,216			272,565			388,111	271,969
Loss per common share, basic and diluted	$ (0.11)			$ (0.12)			$ (0.33)	$ (0.52)

- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

+ References

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+ Details

Loss per common share - Schedule of calculation of diluted net loss per share allocable to common stockholders (Details) - shares shares in Thousands	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	49,327	34,826
Stock options [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	18,413	24,590
RSUs [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	16,118	6,030
PSUs [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	9,669	2,423
Warrant [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount	5,127	1,783

Related parties - Additional Information (Details) - USD ($)	3 Months Ended		9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020	Sep. 30, 2021	Sep. 30, 2020	Dec. 31, 2020
Catalent [Member]
Related Party Transaction [Line Items]
Amount billed	$ 1,100,000	$ 500,000	$ 2,600,000	$ 2,600,000
Catalent [Member] \| Maximum [Member]
Related Party Transaction [Line Items]
Accounts Payable, Related Parties, Current	100,000		100,000		$ 300,000
American International Group [Member]
Related Party Transaction [Line Items]
Amount billed		$ 100,000		$ 200,000
Accounts Payable, Related Parties, Current	$ 0		0		$ 0
American International Group [Member] \| Maximum [Member]
Related Party Transaction [Line Items]
Amount billed			$ 100,000

Business concentrations - Additional Information (Details)	9 Months Ended
	Sep. 30, 2021
Customer Concentration Risk [Member] \| Maximum [Member] \| Revenue [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Customer Concentration Risk [Member] \| Maximum [Member] \| Accounts Receivable [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Customer Concentration Risk [Member] \| Minimum [Member] \| Revenue [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Customer Concentration Risk [Member] \| Minimum [Member] \| Accounts Receivable [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Vendor Concentration Risk [Member] \| Maximum [Member] \| Product purchases [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Vendor Concentration Risk [Member] \| Maximum [Member] \| Accounts Payable [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Vendor Concentration Risk [Member] \| Minimum [Member] \| Product purchases [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%
Vendor Concentration Risk [Member] \| Minimum [Member] \| Accounts Payable [Member]
Concentration Risk [Line Items]
Concentration Risk, Percentage	10.00%

Business concentrations - Summary of Customers with Product Revenue (Details) - Customer Concentration Risk [Member] - Revenue [Member]	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Customer A [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	10.00%	14.00%
Customer B [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	16.00%	8.00%
Customer C [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	18.00%	9.00%
Customer D [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage		8.00%
Customer E [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	12.00%

Business concentrations - Summary of Customers that Accounted for 10% or Greater of Accounts Receivable (Details) - Customer Concentration Risk [Member] - Accounts Receivable [Member]	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
Customer A [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage		17.00%
Customer B [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	22.00%	19.00%
Customer C [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage	32.00%	25.00%
Customer D [Member]
Disclosure Of Customers With Product Revenue and Account Receivable For The Period [Line Items]
Concentration Risk, Percentage		11.00%

Business concentrations - Summary of Vendors with Product Purchases (Details) - Product purchases [Member] - Vendor Concentration Risk [Member]	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2020
Catalent [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	27.00%	39.00%
Vendor A [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	41.00%	18.00%
Vendor B [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	30.00%	36.00%

Business concentrations - Summary of Vendors Accounted for 10% or Greater of Accounts Payable (Details) - Vendor Concentration Risk [Member] - Accounts Payable [Member]	9 Months Ended	12 Months Ended
	Sep. 30, 2021	Dec. 31, 2020
Vendor E [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	15.00%	17.00%
Vendor F [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	23.00%	16.00%
Vendor G [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage		10.00%
Vendor H [Member]
Disclosure Of Vendors With Product Purchases And Accounts Payable For The Periods [Line Items]
Concentration Risk, Percentage	15.00%