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  <xs:import namespace="http://xbrl.sec.gov/ecd/2025" schemaLocation="https://xbrl.sec.gov/ecd/2025/ecd-2025.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/ecd-sub/2025" schemaLocation="https://xbrl.sec.gov/ecd/2025/ecd-sub-2025.xsd"/>
  <xs:import namespace="http://xbrl.sec.gov/dei-sub/2025" schemaLocation="https://xbrl.sec.gov/dei/2025/dei-sub-2025.xsd"/>
  <xs:element name="ScheduleOfLicenseRightsAndOtherIntangibleAssetsNetAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfLicenseRightsAndOtherIntangibleAssetsNetAbstract"/>
  <xs:element name="ScheduleOfOutstandingAndExercisableWarrantsAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfOutstandingAndExercisableWarrantsAbstract"/>
  <xs:element name="ScheduleOfOutstandingAndExercisableOptionsAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfOutstandingAndExercisableOptionsAbstract"/>
  <xs:element name="ScheduleOfRsusAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfRsusAbstract"/>
  <xs:element name="ScheduleOfPsusAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfPsusAbstract"/>
  <xs:element name="ScheduleOfOutstandingSecuritiesAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfOutstandingSecuritiesAbstract"/>
  <xs:element name="ScheduleOfTotalRevenueAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfTotalRevenueAbstract"/>
  <xs:element name="IntangibleAssetsSubjectToAmortizationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_IntangibleAssetsSubjectToAmortizationAbstract"/>
  <xs:element name="IntangibleAssetsNotSubjectToAmortizationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_IntangibleAssetsNotSubjectToAmortizationAbstract"/>
  <xs:element name="RoyaltyReceivableCurrentPortion" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyReceivableCurrentPortion"/>
  <xs:element name="RoyaltyReceivableLongTerm" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyReceivableLongTerm"/>
  <xs:element name="MiscellaneousIncomeExpense" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_MiscellaneousIncomeExpense"/>
  <xs:element name="WriteoffOfPatentsAndTrademarks" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_WriteoffOfPatentsAndTrademarks"/>
  <xs:element name="GoingConcernPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_GoingConcernPolicyTextBlock"/>
  <xs:element name="SignificantAccountingPoliciesPolicyTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_SignificantAccountingPoliciesPolicyTextBlock"/>
  <xs:element name="ScheduleOfClassesOfAssetsAndLiabilitiesOfDiscontinuedOperationsTableTextBlock" type="dtr:textBlockItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ScheduleOfClassesOfAssetsAndLiabilitiesOfDiscontinuedOperationsTableTextBlock"/>
  <xs:element name="DisposalGroupIncludingDiscontinuedOperationGeneralAndAdministrativeExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_DisposalGroupIncludingDiscontinuedOperationGeneralAndAdministrativeExpenses"/>
  <xs:element name="DisposalGroupIncludingDiscontinuedOperationNonOperatingIncomeExpenseNet" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_DisposalGroupIncludingDiscontinuedOperationNonOperatingIncomeExpenseNet"/>
  <xs:element name="PrepaidCapitalizedLegal" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_PrepaidCapitalizedLegal"/>
  <xs:element name="LicensedRightsandOtherIntangibleAssetsScheduleofLicenseRightsandOtherIntangibleAssetsNetDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_LicensedRightsandOtherIntangibleAssetsScheduleofLicenseRightsandOtherIntangibleAssetsNetDetailsTable"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingWeightedAverageExercisePrice" type="dtr:perShareItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingWeightedAverageExercisePrice"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingIntrinsicValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsOutstandingIntrinsicValue"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWeightedAverageRemainingContractualLife" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardNonOptionEquityInstrumentsWeightedAverageRemainingContractualLife"/>
  <xs:element name="StockholdersEquityScheduleofOutstandingandExercisableOptionsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_StockholdersEquityScheduleofOutstandingandExercisableOptionsDetailsTable"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpiredIntrinsicValue" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpiredIntrinsicValue"/>
  <xs:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermExpired" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTermExpired"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumberExpired" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumberExpired"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePriceExpired" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePriceExpired"/>
  <xs:element name="SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValueExpired" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValueExpired"/>
  <xs:element name="ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeExercisableExpired" type="xbrli:durationItemType" abstract="false" xbrli:periodType="instant" nillable="true" substitutionGroup="xbrli:item" id="txmd_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsWeightedAverageRemainingContractualLifeExercisableExpired"/>
  <xs:element name="StockholdersEquityScheduleofRSUsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_StockholdersEquityScheduleofRSUsDetailsTable"/>
  <xs:element name="StockholdersEquityScheduleofPSUsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_StockholdersEquityScheduleofPSUsDetailsTable"/>
  <xs:element name="BusinessBasisofPresentationNewAccountingStandardsandSummaryofSignificantAccountingPoliciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_BusinessBasisofPresentationNewAccountingStandardsandSummaryofSignificantAccountingPoliciesDetailsTable"/>
  <xs:element name="OneTimeMilestonePayments" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_OneTimeMilestonePayments"/>
  <xs:element name="ThresholdNetSalesAmountToDetermineOneTimeMilestonePayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_ThresholdNetSalesAmountToDetermineOneTimeMilestonePayment"/>
  <xs:element name="RoyaltyRateAsPercentageOnNetSales" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyRateAsPercentageOnNetSales"/>
  <xs:element name="ThresholdAnnualNetSalesToDetermineRoyaltyRate" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_ThresholdAnnualNetSalesToDetermineRoyaltyRate"/>
  <xs:element name="TermOfRoyaltyPayments" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_TermOfRoyaltyPayments"/>
  <xs:element name="DecreaseInRoyaltyRateOnProductByProductBasis" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_DecreaseInRoyaltyRateOnProductByProductBasis"/>
  <xs:element name="MinimumAnnualRoyaltyPayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_MinimumAnnualRoyaltyPayment"/>
  <xs:element name="PeriodOfMinimumAnnualRoyaltyPayment" type="xbrli:durationItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_PeriodOfMinimumAnnualRoyaltyPayment"/>
  <xs:element name="InflationRateAdjustedForMinimalAnnualRoyaltyPayment" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_InflationRateAdjustedForMinimalAnnualRoyaltyPayment"/>
  <xs:element name="PurchaseOfTransferredAssetsAndGrantOfLicensesCashPayment" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_PurchaseOfTransferredAssetsAndGrantOfLicensesCashPayment"/>
  <xs:element name="PaymentsToAcquireNetWorkingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_PaymentsToAcquireNetWorkingCapital"/>
  <xs:element name="QuarterlyRoyaltyInterest" type="dtr:percentItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_QuarterlyRoyaltyInterest"/>
  <xs:element name="RoyaltyPaymentPayableUnderLongTermServiceAgreement" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyPaymentPayableUnderLongTermServiceAgreement"/>
  <xs:element name="RoyaltyPaymentHeldBack" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyPaymentHeldBack"/>
  <xs:element name="AdditionalFund" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_AdditionalFund"/>
  <xs:element name="LicensedRightsandOtherIntangibleAssetsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_LicensedRightsandOtherIntangibleAssetsDetailsTable"/>
  <xs:element name="LegalProceedingDomainDomain" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_LegalProceedingDomainDomain"/>
  <xs:element name="CommitmentsandContingenciesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_CommitmentsandContingenciesDetailsTable"/>
  <xs:element name="CashReceivedForNetWorkingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_CashReceivedForNetWorkingCapital"/>
  <xs:element name="AdjustmentOfIncreaseInAccrualOnWorkingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_AdjustmentOfIncreaseInAccrualOnWorkingCapital"/>
  <xs:element name="WorkingCapitalAmounts" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_WorkingCapitalAmounts"/>
  <xs:element name="IncreasedAllowanceForNetWorkingCapital" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="duration" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_IncreasedAllowanceForNetWorkingCapital"/>
  <xs:element name="StockholdersEquityDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_StockholdersEquityDetailsTable"/>
  <xs:element name="RevenueDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_RevenueDetailsTable"/>
  <xs:element name="RelatedPartiesDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_RelatedPartiesDetailsTable"/>
  <xs:element name="StockRedemptionPricePerShares" type="dtr:perShareItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_StockRedemptionPricePerShares"/>
  <xs:element name="NumberofAdditionalSharesOfCommonStock" type="xbrli:sharesItemType" abstract="false" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_NumberofAdditionalSharesOfCommonStock"/>
  <xs:element name="GrossProceedsFromDrawdownBeforeExpenses" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="credit" nillable="true" substitutionGroup="xbrli:item" id="txmd_GrossProceedsFromDrawdownBeforeExpenses"/>
  <xs:element name="BusinessConcentrationsDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_BusinessConcentrationsDetailsTable"/>
  <xs:element name="RoyaltyReceivableShortTermPortion" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyReceivableShortTermPortion"/>
  <xs:element name="RoyaltyReceivableLongTermPortion" type="xbrli:monetaryItemType" abstract="false" xbrli:periodType="instant" xbrli:balance="debit" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyReceivableLongTermPortion"/>
  <xs:element name="SegmentReportingDetailsTable" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:hypercubeItem" id="txmd_SegmentReportingDetailsTable"/>
  <xs:element name="LegalProceedingAxis" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrldt:dimensionItem" id="txmd_LegalProceedingAxis"/>
  <xs:element name="HormoneTherapyDrugPatentsAppliedAndPendingApprovalMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_HormoneTherapyDrugPatentsAppliedAndPendingApprovalMember"/>
  <xs:element name="HormoneTherapyDrugPatentsMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_HormoneTherapyDrugPatentsMember"/>
  <xs:element name="IntangibleAssetsNotSubjectToAmortizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_IntangibleAssetsNotSubjectToAmortizationMember"/>
  <xs:element name="IntangibleAssetsSubjectToAmortizationMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_IntangibleAssetsSubjectToAmortizationMember"/>
  <xs:element name="KnightMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_KnightMember"/>
  <xs:element name="MayneLicenseAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MayneLicenseAgreementMember"/>
  <xs:element name="MaynePharmaAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MaynePharmaAgreementMember"/>
  <xs:element name="MaynePharmaMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MaynePharmaMember"/>
  <xs:element name="MilestonePaymentsOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MilestonePaymentsOneMember"/>
  <xs:element name="MilestonePaymentsThreeMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MilestonePaymentsThreeMember"/>
  <xs:element name="MilestonePaymentsTwoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_MilestonePaymentsTwoMember"/>
  <xs:element name="ParagraphFourCertificationNoticeLetterMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_ParagraphFourCertificationNoticeLetterMember"/>
  <xs:element name="RoyaltyRateOneMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyRateOneMember"/>
  <xs:element name="RoyaltyRateTwoMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_RoyaltyRateTwoMember"/>
  <xs:element name="RubricCapitalManagementLPMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_RubricCapitalManagementLPMember"/>
  <xs:element name="SubscriptionAgreementMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_SubscriptionAgreementMember"/>
  <xs:element name="TheramexMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_TheramexMember"/>
  <xs:element name="TwoThousandNineteenStockIncentivePlanMember" type="dtr:domainItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_TwoThousandNineteenStockIncentivePlanMember"/>
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  <xs:element name="DocumentAndEntityInformationAbstract" type="xbrli:stringItemType" abstract="true" xbrli:periodType="duration" nillable="true" substitutionGroup="xbrli:item" id="txmd_DocumentAndEntityInformationAbstract"/>
</xs:schema>
